SCHEMBL5481577

SCHEMBL5481577

CCOC(=O)C(C)(C)Oc1c(C)cc(CN(CC(=O)O)C(=O)OCC2c3ccccc3-c3ccccc32)cc1C

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 7/20 0.35
PPARG P37231 4/20 0.35
CASP3 P42574 2/20 0.34
KMT2A Q03164 2/20 0.34
FABP5 Q01469 3/20 0.33
FABP7 O15540 2/20 0.33
PPARD Q03181 2/20 0.33
EPHX2 P34913 1/20 0.32
CYP1A2 P05177 2/20 0.32
ABCB11 O95342 1/20 0.32
CYP3A4 P08684 1/20 0.32
TSHR P16473 1/20 0.32
HTR2A P28223 1/20 0.32
PMP22 Q01453 1/20 0.32
TLR7 Q9NYK1 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5477221 0.91 PPARA (0.34) PPARAPPARGKMT2AFABP5FABP7
SCHEMBL5481185 0.88 KMT2A (0.37) PPARAPPARGKMT2AEPHX2
SCHEMBL5472008 0.88 FSHR (0.33) PPARAPPARGKMT2AEPHX2TLR7
SCHEMBL5480676 0.86 KMT2A (0.32) PPARAPPARGKMT2A
SCHEMBL5472110 0.85 PPARA (0.33) PPARAPPARGPPARD
SCHEMBL5482666 0.84 PPARA (0.33) PPARAPPARG
SCHEMBL5484449 0.84 PPARA (0.41) PPARAPPARGPPARDCYP1A2ABCB11
SCHEMBL800081 0.78 KMT2A (0.45) CASP3KMT2AFABP5FABP7EPHX2
SCHEMBL31437116 0.78 KMT2A (0.45) CASP3KMT2AFABP5FABP7EPHX2
SCHEMBL29670345 0.78 KMT2A (0.45) CASP3KMT2AFABP5FABP7EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070208021-A1 Phenoxyacetic Acid Derivatives and Drug Comprising The Same DAIICHI PHARMACEUTICAL CO., LTD. 2007-09-06 US disclosed
US-20070208021-A1 Phenoxyacetic Acid Derivatives and Drug Comprising The Same DAIICHI PHARMACEUTICAL CO., LTD. 2007-09-06 US disclosed
US-20070208021-A1 Phenoxyacetic Acid Derivatives and Drug Comprising The Same DAIICHI PHARMACEUTICAL CO., LTD. 2007-09-06 US disclosed
EP-1731513-A1 PHENOXYACETIC ACID DERIVATIVE AND MEDICINE CONTAINING THE SAME DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2006-12-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070208021-A1 Phenoxyacetic Acid Derivatives and Drug Comprising The Same PPARA, PPARG, PPARD PPARA 1/4885PPARG 2/4885CASP3 2367/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.