Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | GNRHR | P30968 | 7/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.36 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | C1R | P00736 | 1/20 | 0.35 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | NPEPPS | P55786 | 1/20 | 0.34 |
| ▸ | ALPL | P05186 | 1/20 | 0.34 |
| ▸ | ALPI | P09923 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | ALPG | P10696 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5461048 | 0.90 | GNRHR (0.44) | KDM4EHTTGNRHRTP53L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL5467496 | 0.82 | GNRHR (0.38) | KDM4EHTTGNRHRTP53KMT2A | |
| SCHEMBL5473782 | 0.82 | GNRHR (0.49) | KDM4EHTTGNRHRTP53KMT2A | |
| SCHEMBL5464454 | 0.82 | MAPT (0.52) | KDM4EHTTGNRHRTP53KMT2A | |
| Trifluoroacetic Acid SCHEMBL5467389 | 0.80 | GNRHR (0.51) | KDM4EHTTGNRHRTP53KMT2A | |
| Trifluoroacetic Acid SCHEMBL5479474 | 0.79 | MAPT (0.40) | KDM4EHTTKMT2AC1RPRSS1 | |
| SCHEMBL5461789 | 0.78 | KDM4E (0.52) | KDM4EHTTGNRHRTP53KMT2A | |
| SCHEMBL5470082 | 0.78 | RXFP1 (0.53) | KDM4EHTTGNRHRTP53KMT2A | |
| Trifluoroacetic Acid SCHEMBL5461737 | 0.78 | GNRHR (0.40) | KDM4EHTTGNRHRTP53L3MBTL1 | |
| Trifluoroacetic Acid SCHEMBL5474127 | 0.77 | APOBEC3A (0.45) | KDM4EHTTGNRHRTP53KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070010537-A1 | Fused pyramidine derivative and use thereof | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2007-01-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070010537-A1 | Fused pyramidine derivative and use thereof | NR5A1, GNRHR, RXFP3 | KDM4E 4108/4885HTT 2381/4885GNRHR 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.