Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.75 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 2/20 | 0.39 |
| ▸ | GABRP | O00591 | 2/20 | 0.36 |
| ▸ | GABRD | O14764 | 2/20 | 0.36 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.36 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.36 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.36 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.36 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.36 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.36 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.36 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.36 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.36 |
| ▸ | GABRE | P78334 | 2/20 | 0.36 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.36 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.36 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.36 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Valine SCHEMBL9088823 | 0.90 | SLC7A5 (0.75) | SLC7A5SLC1A3SLC1A2SLC1A1GABRP | |
| Valine SCHEMBL9672476 | 0.90 | SLC7A5 (0.75) | SLC7A5SLC1A3SLC1A2SLC1A1GABRP | |
| Valine SCHEMBL28208689 | 0.89 | SLC7A5 (0.60) | SLC7A5SLC1A3SLC1A2SLC1A1GABRP | |
| Valine SCHEMBL6360907 | 0.88 | SLC7A5 (0.71) | SLC7A5SLC1A3SLC1A2SLC1A1GABRP | |
| Valine SCHEMBL10725920 | 0.87 | SLC7A5 (0.79) | SLC7A5SLC1A3SLC1A2SLC1A1GABRP | |
| Valine SCHEMBL167435 | 0.87 | SLC7A5 (0.88) | SLC7A5SLC1A3SLC1A2SLC1A1GABRP | |
| Valine SCHEMBL28760105 | 0.87 | SLC7A5 (0.88) | SLC7A5SLC1A3SLC1A2SLC1A1GABRP | |
| Valine SCHEMBL20981544 | 0.87 | SLC7A5 (0.88) | SLC7A5SLC1A3SLC1A2SLC1A1GABRP | |
| Valine SCHEMBL28747338 | 0.87 | SLC7A5 (0.88) | SLC7A5SLC1A3SLC1A2SLC1A1GABRP | |
| Valine SCHEMBL167437 | 0.87 | SLC7A5 (0.88) | SLC7A5SLC1A3SLC1A2SLC1A1GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 45 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2194145-B1 | Diagnosing and monitoring cardiac transplant rejection based on marker expression level | XDX INC (US) | 2013-06-05 | — | — | EP | disclosed |
| EP-1585972-B1 | USE OF GENE EXPRESSION MARKERS FOR ASSESSING CARDIAC ALLOGRAFT REJECTION | XDX INC (US) | 2013-03-20 | — | — | EP | disclosed |
| EP-2253719-B1 | Diagnosing and monitoring cardiac allograft rejection based on marker expression level | XDX INC (US) | 2013-03-20 | — | — | EP | disclosed |
| EP-2292786-B1 | Diagnosing and monitoring cardiac transplant rejection based on marker expression levels | XDX INC (US) | 2012-10-03 | — | — | EP | disclosed |
| US-8110364-B2 | Methods and compositions for diagnosing or monitoring autoimmune and chronic inflammatory diseases | XDX, INC. (US) | 2012-02-07 | — | — | US | disclosed |
| US-20120010096-A1 | METHODS AND COMPOSITIONS FOR DIAGNOSING AND MONITORING TRANSPLANT REJECTION | XDX, INC. (US) | 2012-01-12 | — | — | US | disclosed |
| US-20110262914-A1 | METHODS AND COMPOSITIONS FOR DIAGNOSING OR MONITORING AUTOIMMUNE AND CHRONIC INFLAMMATORY DISEASES | XDX, INC. (US) | 2011-10-27 | — | — | US | disclosed |
| US-7960121-B2 | Methods and compositions for diagnosing and monitoring transplant rejection | XDX, INC. (US) | 2011-06-14 | — | — | US | disclosed |
| US-20110104697-A1 | METHODS AND COMPOSITIONS FOR DIAGNOSING AND MONITORING TRANSPLANT REJECTION | XDX, INC. (US) | 2011-05-05 | — | — | US | disclosed |
| US-20110070584-A1 | METHODS AND COMPOSITIONS FOR DIAGNOSING AND MONITORING AUTOIMMUNE AND CHRONIC INFLAMMATORY DISEASES | XDX, INC. (US) | 2011-03-24 | — | — | US | disclosed |
| US-20070031890-A1 | Methods and compositions for diagnosing and monitoring transplant rejection | CAREDX, INC. | 2007-02-08 | — | — | US | disclosed |
| US-20060088836-A1 | Methods and compositions for diagnosing and monitoring transplant rejection | CAREDX, INC. | 2006-04-27 | — | — | US | disclosed |
| EP-1585972-A2 | METHODS AND COMPOSITIONS FOR DIAGNOSING AND MONITORING TRANSPLANT REJECTION | Expression Diagnostics, Inc. (US) | 2005-10-19 | — | — | EP | disclosed |
| US-6905827-B2 | Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases | EXPRESSION DIAGNOSTICS, INC. (US) | 2005-06-14 | — | — | US | disclosed |
| WO-2004042346-A2 | METHODS AND COMPOSITIONS FOR DIAGNOSING AND MONITORING TRANSPLANT REJECTION | EXPRESSION DIAGNOSTICS, INC. (US) | 2004-05-21 | — | — | WO | disclosed |
| US-20040009479-A1 | Methods and compositions for diagnosing or monitoring auto immune and chronic inflammatory diseases | CAREDX, INC. | 2004-01-15 | — | — | US | disclosed |
| WO-2003090694-A2 | METHODS AND COMPOSITIONS FOR DIAGNOSING AND MONITORING AUTO IMMUNE AND CHRONIC INFLAMMATORY DISEASES | EXPRESSION DIAGNOSTICS, INC. (US) | 2003-11-06 | — | — | WO | disclosed |
| WO-2002057414-A9 | LEUKOCYTE EXPRESSION PROFILING | EXPRESSION DIAGNOSTICS INC (US) | 2003-09-12 | — | — | WO | disclosed |
| EP-1334113-A2 | LEUKOCYTE EXPRESSION PROFILING | Expression Diagnostics, Inc. (US) | 2003-08-13 | — | — | EP | disclosed |
| WO-2002057414-A2 | LEUKOCYTE EXPRESSION PROFILING | EXPRESSION DIAGNOSTICS, INC. (US) | 2002-07-25 | — | — | WO | disclosed |