Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 2/20 | 0.71 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | GABRP | O00591 | 2/20 | 0.39 |
| ▸ | GABRD | O14764 | 2/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.39 |
| ▸ | GABRE | P78334 | 2/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.39 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.39 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.39 |
| ▸ | SLC1A3 | P43003 | 2/20 | 0.38 |
| ▸ | SLC1A2 | P43004 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Valine SCHEMBL22558018 | 0.98 | SLC7A5 (0.68) | SLC7A5LMNAGABRPGABRDGABRA1 | |
| Valine SCHEMBL30284821 | 0.88 | SLC7A5 (0.68) | SLC7A5LMNAGABRPGABRDGABRA1 | |
| Valine SCHEMBL9603102 | 0.88 | SLC7A5 (0.68) | SLC7A5LMNAGABRPGABRDGABRA1 | |
| Valine SCHEMBL4012840 | 0.88 | SLC7A5 (0.68) | SLC7A5LMNAGABRPGABRDGABRA1 | |
| Valine SCHEMBL547430 | 0.88 | SLC7A5 (0.75) | SLC7A5GABRPGABRDGABRA1GABRB1 | |
| Valine SCHEMBL9672476 | 0.88 | SLC7A5 (0.75) | SLC7A5GABRPGABRDGABRA1GABRB1 | |
| Valine SCHEMBL9088823 | 0.88 | SLC7A5 (0.75) | SLC7A5GABRPGABRDGABRA1GABRB1 | |
| Valine SCHEMBL4498576 | 0.86 | SLC7A5 (0.65) | SLC7A5LMNAGABRPGABRDGABRA1 | |
| Valine SCHEMBL28747338 | 0.85 | SLC7A5 (0.88) | SLC7A5GABRPGABRDGABRA1GABRB1 | |
| Valine SCHEMBL20981544 | 0.85 | SLC7A5 (0.88) | SLC7A5GABRPGABRDGABRA1GABRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111004545-A | Color paste for color 3D printing UV photocuring material and preparation method and application thereof | 北京印刷学院 | 2020-04-14 | — | — | CN | disclosed |
| EP-2570410-B1 | 1-[(4-HYDROXYPRIDIN-4-YL) METHYL]PYRIDINE-2(1H)-ONE DERIVATIVES, PREPARATION METHODS AND USES THEREOF | INST PHARMACOLOGY & TOXICOLOGY ACADEMY MILITARY MEDICAL SCIENCES PLA CHINA (CN) | 2018-11-21 | — | — | EP | disclosed |
| CN-107226812-A | One class piperidines thiazole oxime ether methoxy base acrylate derivative and its production and use | 南开大学 | 2017-10-03 | — | — | CN | disclosed |
| CN-106537557-A | Adhesion layer composition, method for forming film by nanoimprinting, and methods for manufacturing optical component, circuit board and electronic apparatus | 佳能株式会社 | 2017-03-22 | — | — | CN | disclosed |
| US-8921563-B2 | 1-[(4-hydroxypiperidin-4-yl)methyl]pyridin-2(1H)-one derivatives, preparation methods and uses thereof | Institue of Pharmacology and Toxicology Academy of Military Medical Sciences P.L.A., China (CN) | 2014-12-30 | — | — | US | disclosed |
| CN-102241667-B | 1-[(4-hydroxypiperidine-4-yl) methyl] pyridine-2(1H)-one derivatives, preparation method and use thereof | INST PHARM & TOXICOLOGY AMMS | 2013-10-23 | — | — | CN | disclosed |
| US-20130231369-A1 | 1-[(4-hydroxypiperidin-4-yl)methyl]pyridin-2(1H)-one derivatives, preparation methods and uses thereof | INSTITUTE OF PHARMACOLOGY AND TOXICOLOGY ACADEMY OF MILITARY MEDICAL SCIENCES P.L.A. CHINA (CN) | 2013-09-05 | — | — | US | disclosed |
| EP-2570410-A1 | 1-[(4-HYDROXYPRIDIN-4-YL) METHYL]PYRIDINE-2(1H)-ONE DERIVATIVES, PREPARATION METHODS AND USES THEREOF | Institute Of Pharmacology And Toxicology Academy Of Military Medical Sciences P.L.A. China (CN) | 2013-03-20 | — | — | EP | disclosed |
| CN-102241667-A | 1-[(4-hydroxypiperidine-4-yl) methyl] pyridine-2(1H)-one derivatives, preparation method and use thereof | INST PHARM & TOXICOLOGY AMMS | 2011-11-16 | — | — | CN | disclosed |
| CN-1886391-A | Teramic acid and threonine as beta-secretase inhibitors | HOFFMANN LA ROCHE (CH) | 2006-12-27 | — | — | CN | disclosed |
| EP-1385893-A2 | RADIATION CURABLE COATING COMPOSITION | DSM IP Assets B.V. (NL) | 2004-02-04 | — | — | EP | disclosed |
| EP-1353893-A1 | PROCESS FOR THE PREPARATION OF ESTERS OF (METH)ACRYLIC ACID | Dsm N.V. (NL) | 2003-10-22 | — | — | EP | disclosed |
| CN-1434020-A | Process for preparing acrylic ester (methacrylic) | DSM NV (NL) | 2003-08-06 | — | — | CN | disclosed |
| US-20020168164-A1 | Radiation curable coating composition | DSM IP ASSETS B.V. (NL) | 2002-11-14 | — | — | US | disclosed |
| US-20020156317-A1 | Process for the preparation of esters of (meth)acrylic acid | DSM IP ASSETS B.V. (NL) | 2002-10-24 | — | — | US | disclosed |
| WO-2002055473-A1 | PROCESS FOR THE PREPARATION OF ESTERS OF (METH)ACRYLIC ACID | DSM IP ASSETS B.V. (NL) | 2002-07-18 | — | — | WO | disclosed |
| WO-2002055574-A2 | RADIATION CURABLE COATING COMPOSITION | DSM NV (NL) | 2002-07-18 | — | — | WO | disclosed |
| EP-0409623-A1 | Adhesive composition | SOMAR CORPORATION (JP) | 1991-01-23 | — | — | EP | disclosed |
| US-4302460-A | 4-Quinolinones having antihypertensive activity | THE BOOTS COMPANY LIMITED (GB) | 1981-11-24 | — | — | US | disclosed |
| US-4127720-A | ANTIALLERGENS | BRISTOL-MYERS COMPANY (US) | 1978-11-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130231369-A1 | 1-[(4-hydroxypiperidin-4-yl)methyl]pyridin-2(1H)-one derivatives, preparation methods and uses thereof | HTR1A, HTR5A, HTR2C | SLC7A5 872/4885LMNA 1346/4885GABRP 457/4885 |
| US-20020156317-A1 | Process for the preparation of esters of (meth)acrylic acid | ADH1A, PAM, OXGR1 | SLC7A5 2436/4885LMNA 3979/4885GABRP 1222/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.