Chloral Hydrate

Chloral Hydrate

SCHEMBL5474333

CNC(C)=O.OC(O)C(Cl)(Cl)Cl

nearest known ligand 0.50

Full drug profile on Sugi Atlas →

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.50
NFKB1 P19838 2/20 0.34
MEN1 O00255 1/20 0.34
ALDH1A1 P00352 1/20 0.34
MAPT P10636 1/20 0.34
NFKB2 Q00653 1/20 0.34
KMT2A Q03164 1/20 0.34
RELA Q04206 1/20 0.34
CYP2C19 P33261 2/20 0.33
KDM4E B2RXH2 1/20 0.33
CA2 P00918 1/20 0.33
PTGS1 P23219 1/20 0.33
MMP12 P39900 1/20 0.33
HPGD P15428 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chloromethane SCHEMBL10874359 0.82
Isopropyl Alcohol SCHEMBL11113896 0.76
Chloroform SCHEMBL10358242 0.76
SCHEMBL4397 0.74
SCHEMBL20411614 0.74
SCHEMBL2401765 0.74 KDM4E (0.54) LMNANFKB1ALDH1A1KDM4ECA2
SCHEMBL18510170 0.74
SCHEMBL10956055 0.71
Ammonia Solution, Strong SCHEMBL10746719 0.71
Methyl Alcohol SCHEMBL10966612 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070068816-A1 Hydrogel preparation and process of manufacture thereof L 2007-03-29 US disclosed
US-20060127878-A1 Hydrogel preparation and process of manufacture thereof LIFE THERAPEUTICS LIMITED (AU) 2006-06-15 US disclosed
WO-2004055057-A1 HYDROGEL PREPARATION AND PROCESS OF MANUFACTURE THEREOF THE UNIVERSITY OF MELBOURNE (AU) 2004-07-01 WO disclosed