Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.52 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.52 |
| ▸ | FOLH1 | Q04609 | 7/20 | 0.48 |
| ▸ | TET2 | Q6N021 | 3/20 | 0.48 |
| ▸ | KDM4A | O75164 | 2/20 | 0.48 |
| ▸ | KDM4C | Q9H3R0 | 2/20 | 0.48 |
| ▸ | KDM2A | Q9Y2K7 | 2/20 | 0.48 |
| ▸ | TET3 | O43151 | 1/20 | 0.48 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TBXAS1 | P24557 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12838599 | 0.97 | — | — | |
| SCHEMBL6701489 | 0.97 | — | — | |
| SCHEMBL2844312 | 0.97 | — | — | |
| SCHEMBL5466268 | 0.95 | GPR84 (0.52) | GPR84FFAR1FOLH1TET2KDM4A | |
| SCHEMBL5480495 | 0.95 | GPR84 (0.52) | GPR84FFAR1FOLH1TET2KDM4A | |
| SCHEMBL5470511 | 0.95 | GPR84 (0.52) | GPR84FFAR1FOLH1TET2KDM4A | |
| SCHEMBL5466935 | 0.95 | GPR84 (0.52) | GPR84FFAR1FOLH1TET2KDM4A | |
| SCHEMBL5460635 | 0.95 | GPR84 (0.52) | GPR84FFAR1FOLH1TET2KDM4A | |
| SCHEMBL902569 | 0.81 | — | — | |
| SCHEMBL3353937 | 0.81 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070010583-A1 | Methods and compositions for reducing blood homocysteine levels | NOVUS INTERNATIONAL, INC. | 2007-01-11 | — | — | US | claimed |
| WO-2006128048-A2 | METHODS AND COMPOSITIONS FOR REDUCING BLOOD HOMOCYSTEINE LEVELS | NOVUS INTERNATIONAL, INC. (US) | 2006-11-30 | — | — | WO | claimed |
| US-20070010583-A1 | Methods and compositions for reducing blood homocysteine levels | NOVUS INTERNATIONAL, INC. | 2007-01-11 | — | — | US | disclosed |
| WO-2006128048-A2 | METHODS AND COMPOSITIONS FOR REDUCING BLOOD HOMOCYSTEINE LEVELS | NOVUS INTERNATIONAL, INC. (US) | 2006-11-30 | — | — | WO | disclosed |