⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1842192 | 0.90 | TSHR (0.60) | — | |
| SCHEMBL3900888 | 0.82 | — | — | |
| SCHEMBL24513783 | 0.72 | LMNA (0.44) | — | |
| Glutarate SCHEMBL27556904 | 0.72 | SLC22A6 (0.85) | — | |
| Adipic Acid SCHEMBL10388302 | 0.72 | LMNA (0.85) | — | |
| Adipic Acid SCHEMBL11767551 | 0.72 | LMNA (0.85) | — | |
| Glutarate SCHEMBL6701735 | 0.71 | — | — | |
| Glutarate SCHEMBL7414 | 0.71 | — | — | |
| Adipic Acid SCHEMBL2244299 | 0.71 | LMNA (1.00) | — | |
| Adipic Acid SCHEMBL1330953 | 0.71 | LMNA (1.00) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3118277-B1 | METHOD FOR PRODUCING SURFACE-MODIFIED SUBSTRATE, METHOD FOR PRODUCING CONJUGATE, NOVEL HYDROSILANE COMPOUND, SURFACE TREATMENT AGENT, SURFACE TREATMENT AGENT KIT, AND SURFACE-MODIFIED SUBSTRATE | UNIV KYOTO (JP) | 2019-10-23 | — | — | EP | claimed |
| US-20180200273-A1 | Silanol Based Therapeutic Payloads | BLINKBIO INC (US) | 2018-07-19 | — | — | US | disclosed |
| US-9931407-B2 | Silicon based drug conjugates and methods of using same | BLINKBIO, INC. (US) | 2018-04-03 | — | — | US | disclosed |
| US-20170202970-A1 | SILICON BASED DRUG CONJUGATES AND METHODS OF USING SAME | BLINKBIO, INC. | 2017-07-20 | — | — | US | disclosed |
| US-20070090052-A1 | Chromatographic stationary phase | AGILENT TECHNOLOGIES, INC. | 2007-04-26 | — | — | US | disclosed |