SCHEMBL5475152

SCHEMBL5475152

CC1C(Cl)=Cc2ccccc21

nearest known ligand 0.40

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 5/20 0.40
DRD4 P21917 5/20 0.40
BRD4 O60885 1/20 0.39
CCL2 P13500 1/20 0.39
CYP19A1 P11511 1/20 0.33
CYP11B1 P15538 1/20 0.33
CYP11B2 P19099 1/20 0.33
HTR2A P28223 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27933103 0.77 DRD2 (0.37) DRD2DRD4BRD4CCL2CYP19A1
SCHEMBL251288 0.74 DRD2 (0.41) DRD2DRD4BRD4CCL2CYP19A1
SCHEMBL9124724 0.74 HTR2A (0.31) HTR2A
SCHEMBL29458545 0.74 DRD2 (0.41) DRD2DRD4BRD4CCL2CYP19A1
SCHEMBL28417072 0.74 HTR2A (0.33) HTR2A
SCHEMBL9148116 0.73 DRD2 (0.40) DRD2DRD4BRD4CCL2CYP19A1
SCHEMBL813597 0.73 DRD2 (0.40) DRD2DRD4BRD4CCL2CYP19A1
Hydrochloric Acid SCHEMBL3209890 0.73 HTR2A (0.30) CYP19A1CYP11B1CYP11B2HTR2A
SCHEMBL5574454 0.73 DRD2 (0.40) DRD2DRD4BRD4CCL2CYP19A1
Lithium SCHEMBL9145416 0.73 DRD2 (0.40) DRD2DRD4BRD4CCL2CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7186783-B2 Process for preparaing partially hydrogenated butadiene polymers KRATON POLYMERS U.S. LLC (US) 2007-03-06 US disclosed
EP-1311561-B1 PROCESS FOR PREPARING PARTIALLY HYDROGENATED BUTADIENE POLYMERS KRATON POLYMERS RES BV (NL) 2005-06-08 EP disclosed
US-20030092851-A1 Process for preparing partially hydrogenated butadiene polymers BANK OF AMERICA, N.A. 2003-05-15 US disclosed