SCHEMBL5475366

SCHEMBL5475366

CC(=O)c1c(O)c(Br)c(C(C)=O)c(O)c1Br

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.40
HPGD P15428 3/20 0.40
THRB P10828 1/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
PTPN1 P18031 2/20 0.35
CA12 O43570 2/20 0.35
CA9 Q16790 2/20 0.35
ALDH1A1 P00352 3/20 0.35
ALOX15 P16050 2/20 0.35
HIF1A Q16665 2/20 0.35
HSD17B10 Q99714 2/20 0.35
MAPK1 P28482 2/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA4 P22748 1/20 0.35
CA6 P23280 1/20 0.35
RECQL P46063 1/20 0.35
PRKCI P41743 1/20 0.33
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16723871 0.78 PTPN1 (0.42) CYP3A4HPGDTHRBMEN1KMT2A
SCHEMBL14346937 0.75 PTPN1 (0.40) CYP3A4HPGDTHRBMEN1KMT2A
SCHEMBL25384697 0.74 PTPN1 (0.52) CYP3A4PTPN1CA12CA9MAPK1
SCHEMBL6023652 0.74 CYP3A4 (0.48) CYP3A4HPGDTHRBMEN1KMT2A
SCHEMBL28858193 0.73 MEN1 (0.48) CYP3A4HPGDTHRBMEN1KMT2A
SCHEMBL5633583 0.71 CA9 (0.47) CYP3A4HPGDMEN1KMT2ACA12
SCHEMBL28117211 0.69 CYP3A4 (0.43) CYP3A4HPGDTHRBMEN1KMT2A
SCHEMBL7094683 0.69 GPR35 (0.38) CYP3A4HPGDTHRBMEN1KMT2A
SCHEMBL25383713 0.68 PTPN1 (0.50) CYP3A4PTPN1CA12CA9CA2
SCHEMBL12835246 0.67 F2 (0.38) CYP3A4HPGDTHRBMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7169325-B2 Liquid crystalline compound, liquid crystalline composition and retardation film FUJI PHOTO FILM CO., LTD. (JP) 2007-01-30 US disclosed
US-20050012071-A1 Liquid crystalline compound, liquid crystalline composition and retardation film FUJI PHOTO FILM CO., LTD. (JP) 2005-01-20 US disclosed