Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 19/20 | 0.58 |
| ▸ | PRSS1 | P07477 | 5/20 | 0.40 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.40 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8292993 | 0.90 | F2 (0.47) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL5479610 | 0.81 | F2 (0.57) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL5471641 | 0.76 | ATM (0.38) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL5474694 | 0.76 | F2 (0.64) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL5478498 | 0.75 | TLR9 (0.48) | — | |
| SCHEMBL5479621 | 0.75 | ATM (0.39) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL5475869 | 0.74 | F2 (0.39) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7139116 | 0.73 | KDM4E (0.45) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL5474631 | 0.73 | F2 (0.52) | F2PRSS1PRSS2PRSS3 | |
| SCHEMBL8292959 | 0.72 | F2 (0.60) | F2PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070099927-A1 | Aminoalkyl-pyrazinones and-pyridones as thrombin inhibitors | SANTHERA PHARMACEUTICALS (SCHWEIZ) GMBH (CH) | 2007-05-03 | — | — | US | disclosed |
| WO-2005040137-A1 | AMINOALKYL-PYRAZINONES AND -PYRIDONES AS THROMBIN INHIBITORS | SANTHERA PHARMACEUTICALS (SCHWEIZ) GMBH (CH) | 2005-05-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099927-A1 | Aminoalkyl-pyrazinones and-pyridones as thrombin inhibitors | F2, F12, SERPINC1 | F2 1/4885PRSS1 67/4885PRSS2 157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.