⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL972784 | 0.94 | — | — | |
| SCHEMBL2608 | 0.87 | — | — | |
| SCHEMBL596610 | 0.77 | — | — | |
| SCHEMBL10211088 | 0.69 | TDP1 (0.40) | — | |
| SCHEMBL16203348 | 0.69 | TDP1 (0.40) | — | |
| SCHEMBL152779 | 0.69 | TDP1 (0.40) | — | |
| N-Methyl Pyrrolidine (Nmp) SCHEMBL4645 | 0.69 | — | — | |
| N-Methyl Pyrrolidine (Nmp) SCHEMBL37881 | 0.69 | — | — | |
| SCHEMBL13864423 | 0.69 | TDP1 (0.35) | — | |
| N-Methyl Pyrrolidine (Nmp) SCHEMBL3628998 | 0.69 | TDP1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1258 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024051766-A1 | MOLECULAR GLUE COMPOUND BASED ON CEREBLON PROTEIN DESIGN AND USE THEREOF | 标新生物医药科技(上海)有限公司 | 2024-03-14 | — | — | WO | claimed |
| US-20230348453-A1 | HALOGENATED-HETEROARYL AND OTHER HETEROCYCLIC KINASE INHIBITORS, AND USES THEREOF | IOMX THERAPEUTICS AG (DE) | 2023-11-02 | — | — | US | claimed |
| CN-111686110-B | Compounds and compositions for modulating EGFR mutant kinase activity | 株式会社柳韩洋行 | 2023-06-16 | — | — | CN | claimed |
| WO-2023091229-A1 | SMALL MOLECULE BINDERS OF THE ONCOGENIC FUSION TRANSCRIPTION FACTOR PAX3-FOXO1 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2023-05-25 | — | — | WO | claimed |
| US-20230149552-A1 | Small Molecule Binders of the Oncogenic Fusion Transcription Factor PAX3-FOXO1 | MASSACHUSETTS INSTITUTE OF TECHNOLOGY | 2023-05-18 | — | — | US | claimed |
| CN-111606883-B | Sulfur-containing compound based on glutarimide skeleton and application thereof | 上海科技大学 | 2023-05-09 | — | — | CN | claimed |
| EP-4139305-A1 | HALOGENATED-HETEROARYL AND OTHER HETEROCYCLIC KINASE INHIBITORS, AND USES THEREOF | iOmx Therapeutics AG (DE) | 2023-03-01 | — | — | EP | claimed |
| CN-115667255-A | Halogenated heteroaryl and other heterocyclic kinase inhibitors and uses thereof | 艾欧麦克斯治疗股份公司 | 2023-01-31 | — | — | CN | claimed |
| US-20220143002-A1 | SULFUR-CONTAINING COMPOUND BASED ON GLUTARIMIDE SKELETON AND APPLICATION THEREOF | SHANGHAITECH UNIVERSITY (CN) | 2022-05-12 | — | — | US | claimed |
| EP-3932922-A1 | SULFUR-CONTAINING COMPOUND BASED ON GLUTARIMIDE SKELETON AND APPLICATION THEREOF | ShanghaiTech University (CN) | 2022-01-05 | — | — | EP | claimed |
| US-4376773-A | SEDATIVES, HYPNOTICS | BASF AKTIENGESELLSCHAFT (DE) | 1983-03-15 | — | — | US | claimed |
| US-4369321-A | Piperidine derivatives which are stabilizers for synthetic polymers | CHIMOSA CHIMICA ORGANICA S.P.A. (IT) | 1983-01-18 | — | — | US | claimed |
| US-4363816-A | TREATMENT OF GASTROINTESTINAL DISORDERS | BYK GULDEN LOMBERG CHEMISCHE FABRIK GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1982-12-14 | — | — | US | claimed |
| US-4362727-A | SEDATIVES, HYPNOTICS, TRANQUILIZERS, NEUROLEPTICS, ANTIPARKINSON | BASF AKTIENGESELLSCHAFT (DE) | 1982-12-07 | — | — | US | claimed |
| EP-0050212-A1 | 5-Substituted-9-cyane-methylene-dithieno(3,4-b:4',3'-e) azepines, process for their preparation and pharmaceutical compositions containing them | BASF Aktiengesellschaft (DE) | 1982-04-28 | — | — | EP | claimed |
| EP-0035711-A2 | 10-Substituted-5-cyanomethylene-dibenzo-(a,d)cycloheptenes, process for their preparation and pharmaceutical compositions containing them | BASF Aktiengesellschaft (DE) | 1981-09-16 | — | — | EP | claimed |
| EP-0035714-A2 | 10-Substituted-5-cyanomethylene-10,11-dihydro-dibenzo-(a,d)-cycloheptenes, process for their preparation and pharmaceutical compositions containing them | BASF Aktiengesellschaft (DE) | 1981-09-16 | — | — | EP | claimed |
| EP-0019172-A1 | 6-Substituted 11-alkylene-morphantridines, process for preparing them and pharmaceutical compositions containing them | BASF Aktiengesellschaft (DE) | 1980-11-26 | — | — | EP | claimed |
| US-3951982-A | Trialkylsilyl esters of 6(substituted amino)phenyl-1,-dihydro-2-oxonicotinic acid, methods for their production and conversion to the corresponding acid chlorides | PARKE, DAVIS & COMPANY | 1976-04-20 | — | — | US | claimed |
| US-3946015-A | Process for the preparation of acid chlorides | PARKE, DAVIS & COMPANY (US) | 1976-03-23 | — | — | US | claimed |