⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL54757 | 0.94 | — | — | |
| SCHEMBL596610 | 0.81 | — | — | |
| SCHEMBL2608 | 0.79 | — | — | |
| SCHEMBL152779 | 0.73 | TDP1 (0.40) | — | |
| N-Methyl Pyrrolidine (Nmp) SCHEMBL37881 | 0.73 | — | — | |
| SCHEMBL13864423 | 0.73 | TDP1 (0.35) | — | |
| N-Methyl Pyrrolidine (Nmp) SCHEMBL4645 | 0.73 | — | — | |
| SCHEMBL16203348 | 0.73 | TDP1 (0.40) | — | |
| SCHEMBL10211088 | 0.73 | TDP1 (0.40) | — | |
| N-Methyl Pyrrolidine (Nmp) SCHEMBL3628998 | 0.73 | TDP1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8524896-B2 | Chemical compounds | SYNGENTA CROP PROTECTION LLC (US) | 2013-09-03 | — | — | US | disclosed |
| US-20110009261-A1 | CHEMICAL COMPOUNDS | SYNGENTA CROP PROTECTION, INC. (US) | 2011-01-13 | — | — | US | disclosed |
| EP-2265579-A2 | 2-CYANOBENZENSULFONAMIDE DERIVATIVES HAVING PESTICIDAL PROPERTIES | Syngenta Participations AG (CH) | 2010-12-29 | — | — | EP | disclosed |
| WO-2009109539-A2 | CHEMICAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2009-09-11 | — | — | WO | disclosed |
| EP-0551993-B1 | Pyrrolidine derivatives and process for preparing the same | SUMITOMO PHARMA (JP) | 1996-07-10 | — | — | EP | disclosed |
| US-5322952-A | Pyrrolidine derivatives and process for preparing the same | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1994-06-21 | — | — | US | disclosed |
| EP-0551993-A1 | Pyrrolidine derivatives and process for preparing the same | SUMITOMO PHARMACEUTICALS COMPANY, LIMITED (JP) | 1993-07-21 | — | — | EP | disclosed |