Ethylene Glycol

Ethylene Glycol

SCHEMBL5476136

O=C(O)Oc1ccc([N+](=O)[O-])cc1.OCCO

nearest known ligand 0.58

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL9 O00512 1/20 0.57
CTNNB1 P35222 1/20 0.57
GAA P10253 1/20 0.56
SRD5A2 P31213 2/20 0.53
KMT2A Q03164 2/20 0.51
PKM P14618 1/20 0.51
ALDH1A1 P00352 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
MGLL Q99685 2/20 0.50
TSHR P16473 1/20 0.50
MEN1 O00255 1/20 0.49
TDP1 Q9NUW8 1/20 0.48
PTPN7 P35236 1/20 0.48
PTPN12 Q05209 1/20 0.48
PTPN22 Q9Y2R2 1/20 0.48
CA1 P00915 1/20 0.47
CA2 P00918 1/20 0.47
CES2 O00748 1/20 0.47
CES1 P23141 1/20 0.47
MAPT P10636 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26375 0.93 GAA (0.62) BCL9CTNNB1GAASRD5A2KMT2A
Alcohol SCHEMBL23927970 0.91 BCL9 (0.64) BCL9CTNNB1GAASRD5A2KMT2A
Hydrochloric Acid SCHEMBL7895039 0.91 GAA (0.61) BCL9CTNNB1GAASRD5A2KMT2A
Bicarbonate SCHEMBL7985678 0.91 GAA (0.61) BCL9CTNNB1GAASRD5A2KMT2A
Bromide SCHEMBL30468845 0.91 GAA (0.61) BCL9CTNNB1GAASRD5A2KMT2A
Ethylene Glycol SCHEMBL5476146 0.87 BCL9 (0.58) BCL9CTNNB1GAAKMT2APKM
Acetic Acid SCHEMBL28965273 0.87 GAA (0.62) BCL9CTNNB1GAASRD5A2KMT2A
Bicarbonate SCHEMBL9330234 0.87 GAA (0.57) BCL9CTNNB1GAASRD5A2KMT2A
SCHEMBL26654348 0.87 GAA (0.57) BCL9CTNNB1GAASRD5A2KMT2A
Cyclohexane SCHEMBL30739999 0.87 GAA (0.57) BCL9CTNNB1GAASRD5A2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2007047997-A2 METHODS FOR REDUCING THE MITOGENICITY OF LECTIN COMPOSITIONS SMARTCELLS, INC. (US) 2007-04-26 WO disclosed