⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7946817 | 0.75 | — | — | |
| SCHEMBL7028994 | 0.71 | — | — | |
| SCHEMBL9489008 | 0.71 | — | — | |
| SCHEMBL6358981 | 0.67 | — | — | |
| SCHEMBL5476601 | 0.67 | — | — | |
| SCHEMBL7282901 | 0.67 | — | — | |
| SCHEMBL6580989 | 0.67 | — | — | |
| SCHEMBL17707858 | 0.67 | — | — | |
| SCHEMBL3388741 | 0.67 | — | — | |
| SCHEMBL7445251 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1083980-B1 | MODULATION OF MOLECULAR INTERACTION SITES ON RNA AND OTHER BIOMOLECULES | ISIS PHARMACEUTICALS INC (US) | 2007-03-21 | — | — | EP | disclosed |
| US-6969763-B1 | Molecular interaction sites of interleukin-2 RNA and methods of modulating the same | ISIS PHARMACEUTICALS, INC. (US) | 2005-11-29 | — | — | US | disclosed |
| EP-1077993-A4 | GENERATION OF COMBINATORIAL LIBRARIES OF COMPOUNDS CORRESPONDING TO VIRTUAL LIBRARIES OF COMPOUNDS | ISIS PHARMACEUTICALS INC (US) | 2004-09-08 | — | — | EP | disclosed |
| US-20030017483-A1 | Modulation of molecular interaction sites on RNA and other biomolecules | ISIS PHARMACEUTICALS, INC. | 2003-01-23 | — | — | US | disclosed |
| EP-1083980-A2 | MODULATION OF MOLECULAR INTERACTION SITES ON RNA AND OTHER BIOMOLECULES | ISIS PHARMACEUTICALS, INC. (US) | 2001-03-21 | — | — | EP | disclosed |
| EP-1077993-A1 | GENERATION OF COMBINATORIAL LIBRARIES OF COMPOUNDS CORRESPONDING TO VIRTUAL LIBRARIES OF COMPOUNDS | ISIS PHARMACEUTICALS, INC. (US) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058947-A9 | MODULATION OF MOLECULAR INTERACTION SITES ON RNA AND OTHER BIOMOLECULES | ISIS PHARMACEUTICALS INC (US) | 2000-04-20 | — | — | WO | disclosed |
| WO-1999058474-A9 | GENERATION OF COMBINATORIAL LIBRARIES OF COMPOUNDS CORRESPONDING TO VIRTUAL LIBRARIES OF COMPOUNDS | ISIS PHARMACEUTICALS INC (US) | 2000-02-03 | — | — | WO | disclosed |
| WO-1999058947-A2 | MODULATION OF MOLECULAR INTERACTION SITES ON RNA AND OTHER BIOMOLECULES | ISIS PHARMACEUTICALS, INC. (US) | 1999-11-18 | — | — | WO | disclosed |
| WO-1999058474-A1 | GENERATION OF COMBINATORIAL LIBRARIES OF COMPOUNDS CORRESPONDING TO VIRTUAL LIBRARIES OF COMPOUNDS | ISIS PHARMACEUTICALS, INC. (US) | 1999-11-18 | — | — | WO | disclosed |