⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17707858 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL6371396 | 0.68 | — | — | |
| SCHEMBL3752206 | 0.67 | — | — | |
| SCHEMBL2454331 | 0.67 | KDM4E (0.32) | — | |
| SCHEMBL9243400 | 0.67 | — | — | |
| SCHEMBL14538452 | 0.67 | — | — | |
| SCHEMBL5476522 | 0.67 | — | — | |
| SCHEMBL6423181 | 0.62 | — | — | |
| SCHEMBL7068841 | 0.62 | — | — | |
| SCHEMBL472757 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2166002-A1 | Chiral organic catalysts for the enantioselective reduction of n-alkyl and n-benzyl-substituted alicyclic and cyclic imines | UNIVERSITA'DEGLI STUDI DI MILANO (IT) | 2010-03-24 | — | — | EP | disclosed |
| US-7635693-B2 | Methods for preventing and treating cancer using N-thiolated β-lactam compounds and analogs thereof | UNIVERSITY OF SOUTH FLORIDA (US) | 2009-12-22 | — | — | US | disclosed |
| WO-2009068284-A2 | PROCESS FOR THE STEREOSELECTIVE REDUCTION OF KETOIMINES CATALYSED BY TRICHLOROSILANE | UNIVERSITA DEGLI STUDI DI MILANO (IT) | 2009-06-04 | — | — | WO | disclosed |
| EP-2065371-A1 | Chiral organic catalysts for the stereoselective reduction of carbon-nitrogen double bonds for the preparation of enantiomerically enriched amines | UNIVERSITA'DEGLI STUDI DI MILANO (IT) | 2009-06-03 | — | — | EP | disclosed |
| US-20060160787-A1 | Methods for preventing and treating cancer using N-thiolated beta-lactam compounds and analogs thereof | DOU Q P | 2006-07-20 | — | — | US | disclosed |
| US-20060079719-A1 | Aminated compounds bearing at least an allyl and a difluoromethyl and method used for synthesis thereof | RHODIA CHIMIE (FR) | 2006-04-13 | — | — | US | disclosed |
| US-7026472-B2 | Methods for preventing and treating cancer using N-thiolated β-lactam compounds and analogs thereof | UNIVERSITY OF SOUTH FLORIDA (US) | 2006-04-11 | — | — | US | disclosed |
| US-6946458-B2 | N-thiolated beta-lactams: novel antibacterial agents for methicillin-resistant Staphylococcus aureus | UNIVERSITY OF SOUTH FLORIDA (US) | 2005-09-20 | — | — | US | disclosed |
| WO-2004100888-A2 | N-THIOLATED AZETIDINONES AND ANTI-CANCER USE THEREOF | UNIVERSITY OF SOUTH FLORIDA (US) | 2004-11-25 | — | — | WO | disclosed |
| US-20040167115-A1 | Methods for preventing and treating cancer using N-thiolated beta-lactam compounds and analogs thereof | SOUTH FLORIDA, UNIVERSITY OF | 2004-08-26 | — | — | US | disclosed |
| US-20030191108-A1 | N-thiolated beta-lactams: novel antibacterial agents for methicillin-resistant staphylococcus aureus | SOUTH FLORIDA, UNIVERSITY OF | 2003-10-09 | — | — | US | disclosed |