Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TOP1 | P11387 | 1/20 | 0.38 |
| ▸ | ELANE | P08246 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA7 | P43166 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21530764 | 0.84 | PDCD1 (0.32) | TDP1 | |
| SCHEMBL9405344 | 0.82 | IDO1 (0.48) | ALDH1A1MAPTMEN1KMT2AIDO1 | |
| SCHEMBL720169 | 0.76 | CYP3A4 (0.38) | KMT2ATDP1 | |
| SCHEMBL13324254 | 0.76 | CYP3A4 (0.38) | TDP1 | |
| SCHEMBL5398197 | 0.76 | ABCB1 (0.40) | MEN1KMT2AIDO1TAAR1CHRM2 | |
| SCHEMBL14050273 | 0.75 | CA1 (0.44) | ALDH1A1MAPTKDM4ETDP1IDO1 | |
| SCHEMBL12050455 | 0.74 | IDO1 (0.41) | ALDH1A1MAPTMEN1KMT2AIDO1 | |
| SCHEMBL29695439 | 0.74 | CYP3A4 (0.36) | KMT2ATDP1 | |
| Potassium SCHEMBL30843013 | 0.74 | CYP3A4 (0.36) | KMT2ATDP1 | |
| Phosphine SCHEMBL29173742 | 0.74 | CYP3A4 (0.36) | KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7160835-B2 | 2,2'-bis(diphenylphosphinomethyl)diphenyl ethers compleed with rhodium, cobalt, ruthenium or iron compounds as hydroformylation catalysts for the hydroformylation of ethylenically unsaturated compounds; by-product inhibition; improved industrial scale reaction rates | KURARAY CO., LTD. (JP) | 2007-01-09 | — | — | US | disclosed |
| US-20050164874-A1 | 2,2'-bis(diphenylphosphinomethyl)diphenyl ethers compleed with rhodium, cobalt, ruthenium or iron compounds as hydroformylation catalysts for the hydroformylation of ethylenically unsaturated compounds; by-product inhibition; improved industrial scale reaction rates | KURARAY CO., LTD. (JP) | 2005-07-28 | — | — | US | disclosed |
| EP-1489087-A1 | BISPHOSPHINE, PROCESS FOR PRODUCING THE SAME, AND USE THEREOF | Kuraray Co., Ltd. (JP) | 2004-12-22 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050164874-A1 | 2,2'-bis(diphenylphosphinomethyl)diphenyl ethers compleed with rhodium, cobalt, ruthenium or iron compounds as hydroformylation catalysts for the hydroformylation of ethylenically unsaturated compounds; by-product inhibition; improved industrial scale reaction rates | RPIA, ESR2, CBR1 | TOP1 456/4885ELANE 3518/4885ALDH1A1 272/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.