Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 2/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.45 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MMP1 | P03956 | 1/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.44 |
| ▸ | MMP3 | P08254 | 1/20 | 0.44 |
| ▸ | MMP13 | P45452 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5477620 | 1.00 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL5483707 | 0.89 | ALDH1A1 (0.46) | ALDH1A1RAB9ANPC1LMNACYP1A2 | |
| SCHEMBL5483702 | 0.89 | ALDH1A1 (0.46) | ALDH1A1RAB9ANPC1LMNACYP1A2 | |
| SCHEMBL5476038 | 0.87 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL5476042 | 0.87 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL5476044 | 0.87 | ALDH1A1 (0.47) | ALDH1A1SMN1; SMN2RAB9ANPC1LMNA | |
| SCHEMBL5465983 | 0.86 | ALDH1A1 (0.53) | ALDH1A1OPRL1KCNH2MEN1KMT2A | |
| SCHEMBL5465979 | 0.86 | ALDH1A1 (0.53) | ALDH1A1OPRL1KCNH2MEN1KMT2A | |
| SCHEMBL5470962 | 0.86 | ALDH1A1 (0.53) | ALDH1A1OPRL1KCNH2MEN1KMT2A | |
| SCHEMBL5466116 | 0.83 | ALDH1A1 (0.48) | ALDH1A1RAB9ANPC1TSHRMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070078120-A1 | Novel piperidine derivative | DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) | 2007-04-05 | — | — | US | disclosed |
| EP-1679069-A1 | NOVEL PIPERIDINE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2006-07-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070078120-A1 | Novel piperidine derivative | LDLR, PRMT5, MSR1 | ALDH1A1 2990/4885SMN1; SMN2 4689/4885RAB9A 1776/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.