Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.53 |
| ▸ | BRD4 | O60885 | 4/20 | 0.50 |
| ▸ | TTR | P02766 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.48 |
| ▸ | RAB9A | P51151 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.48 |
| ▸ | PTPRC | P08575 | 1/20 | 0.47 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.47 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5478760 | 0.86 | PTPRC (0.61) | ALDH1A1L3MBTL1KDM4EHSD17B10NPC1 | |
| SCHEMBL30452106 | 0.82 | KDM4E (0.57) | ALDH1A1MAPK1HTTL3MBTL1KDM4E | |
| SCHEMBL791852 | 0.78 | HTT (0.86) | ALDH1A1MAPK1HTTL3MBTL1TTR | |
| SCHEMBL7447151 | 0.77 | NCOA1 (0.59) | ALDH1A1MAPK1HTTL3MBTL1PTGS2 | |
| SCHEMBL10711068 | 0.76 | NCOA1 (0.69) | ALDH1A1MAPK1HTTL3MBTL1PTGS2 | |
| SCHEMBL1958156 | 0.76 | NCOA1 (0.74) | MAPK1PTGS2BRD4RAB9ATSHR | |
| SCHEMBL20311734 | 0.75 | PTPRC (0.50) | ALDH1A1L3MBTL1KDM4EHSD17B10NPC1 | |
| SCHEMBL3893284 | 0.75 | NCOA1 (0.58) | FYNPTGS2BRD4TSHRNCOA1 | |
| SCHEMBL5465021 | 0.75 | KIT (0.60) | ALDH1A1L3MBTL1KDM4EHSD17B10NPC1 | |
| SCHEMBL7038165 | 0.75 | L3MBTL1 (0.55) | FYNALDH1A1MAPK1HTTL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070287738-A1 | Substituted Cyanopyridines as protein kinase inhibitors | WYETH | 2007-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287738-A1 | Substituted Cyanopyridines as protein kinase inhibitors | CNKSR1, MAP3K1, MAP3K6 | FYN 823/4885ALDH1A1 3084/4885MAPK1 28/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.