Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHEK1 | O14757 | 17/20 | 0.41 |
| ▸ | ACHE | P22303 | 3/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5475543 | 0.89 | CHEK1 (0.40) | CHEK1ACHEBCHE | |
| SCHEMBL5470779 | 0.81 | CHEK1 (0.51) | CHEK1 | |
| SCHEMBL5474976 | 0.80 | CHEK1 (0.37) | CHEK1ACHEBCHE | |
| SCHEMBL5477789 | 0.78 | ACHE (0.43) | CHEK1ACHEBCHE | |
| SCHEMBL5476394 | 0.76 | CHEK1 (0.54) | CHEK1 | |
| SCHEMBL5483204 | 0.75 | CHEK1 (0.44) | CHEK1 | |
| SCHEMBL5469648 | 0.74 | CHEK1 (0.55) | CHEK1 | |
| SCHEMBL5470122 | 0.72 | CHEK1 (0.51) | CHEK1 | |
| SCHEMBL5469663 | 0.72 | CHEK1 (0.48) | CHEK1 | |
| SCHEMBL5470840 | 0.70 | CHEK1 (0.58) | CHEK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070149560-A1 | Novel fused triazolones and the uses thereof | ASTRAZENECA AB (SE) | 2007-06-28 | — | — | US | claimed |
| US-20070149560-A1 | Novel fused triazolones and the uses thereof | ASTRAZENECA AB (SE) | 2007-06-28 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070149560-A1 | Novel fused triazolones and the uses thereof | TP53, BRCA1, KLK3 | CHEK1 13/4885ACHE 4539/4885BCHE 2981/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.