SCHEMBL5478495

SCHEMBL5478495

COc1cc2cc(Br)ccc2c(-c2c(OC)ccc3cc(Br)ccc23)c1OC

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 6/20 0.45
RXFP1 Q9HBX9 5/20 0.45
POLB P06746 2/20 0.45
MAPT P10636 3/20 0.45
IDO1 P14902 1/20 0.44
TDO2 P48775 1/20 0.44
SMN1; SMN2 Q16637 3/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
KDM4E B2RXH2 2/20 0.40
MEN1 O00255 1/20 0.40
KMT2A Q03164 1/20 0.40
NCEH1 Q6PIU2 2/20 0.40
TUBB4A P04350 1/20 0.40
TUBB P07437 1/20 0.40
TUBA3C P0DPH7 1/20 0.40
TUBA1B P68363 1/20 0.40
TUBA4A P68366 1/20 0.40
TUBB4B P68371 1/20 0.40
TUBB3 Q13509 1/20 0.40
TUBB2A Q13885 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3829305 0.89 MAPT (0.55) LMNARXFP1POLBMAPTIDO1
SCHEMBL30638066 0.89 MAPT (0.55) LMNARXFP1POLBMAPTIDO1
SCHEMBL5749500 0.80 IDO1 (0.57) LMNARXFP1POLBMAPTIDO1
SCHEMBL7670033 0.80 MEN1 (0.52) LMNARXFP1POLBMAPTSMN1; SMN2
SCHEMBL6130225 0.80 MAPT (0.73) MAPTIDO1TDO2SMN1; SMN2KDM4E
SCHEMBL29262562 0.77 MAPT (0.50) LMNARXFP1POLBMAPTIDO1
SCHEMBL8000222 0.77 POLB (0.52) LMNARXFP1POLBMAPTSMN1; SMN2
SCHEMBL3019686 0.75 NCEH1 (0.58) LMNARXFP1POLBMAPTIDO1
SCHEMBL29794205 0.74 MAPT (0.55) POLBMAPTIDO1TDO2SMN1; SMN2
SCHEMBL8502354 0.74 CYP2A6 (0.50) LMNARXFP1POLBMAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070287821-A1 Synthesis of Polynaphthalenes and Their Use BASF AKTIENGESELLSCHAFT (DE) 2007-12-13 US disclosed
EP-1791889-A1 SYNTHESIS OF POLYNAPHTHALENES AND THEIR USE BASF AKTIENGESELLSCHAFT (DE) 2007-06-06 EP disclosed
WO-2006027191-A1 SYNTHESIS OF POLYNAPHTHALENES AND THEIR USE BASF AKTIENGESELLSCHAFT (DE) 2006-03-16 WO disclosed