Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 10/20 | 0.50 |
| ▸ | ADRA2B | P18089 | 4/20 | 0.43 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 6/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 5/20 | 0.41 |
| ▸ | LMNA | P02545 | 5/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 5/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 5/20 | 0.41 |
| ▸ | HTR2C | P28335 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 4/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.41 |
| ▸ | HTR2A | P28223 | 3/20 | 0.41 |
| ▸ | HRH1 | P35367 | 3/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 3/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5478630 | 1.00 | SLC6A4 (0.50) | SLC6A4ADRA2BADRA2AADRA2CSLC6A2 | |
| Hydrochloric Acid SCHEMBL5476841 | 0.99 | SLC6A4 (0.49) | SLC6A4ADRA2BADRA2AADRA2CSLC6A2 | |
| Hydrochloric Acid SCHEMBL5476840 | 0.99 | SLC6A4 (0.49) | SLC6A4ADRA2BADRA2AADRA2CSLC6A2 | |
| Hydrochloric Acid SCHEMBL5476834 | 0.99 | SLC6A4 (0.49) | SLC6A4ADRA2BADRA2AADRA2CSLC6A2 | |
| SCHEMBL5471070 | 0.87 | SLC6A4 (0.46) | SLC6A4ADRA2BADRA2ASLC6A2KMT2A | |
| SCHEMBL5471075 | 0.87 | SLC6A4 (0.46) | SLC6A4ADRA2BADRA2ASLC6A2KMT2A | |
| SCHEMBL5471072 | 0.87 | SLC6A4 (0.46) | SLC6A4ADRA2BADRA2ASLC6A2KMT2A | |
| Hydrochloric Acid SCHEMBL5480418 | 0.86 | SLC6A4 (0.46) | SLC6A4ADRA2BADRA2ASLC6A2KMT2A | |
| Hydrochloric Acid SCHEMBL5480419 | 0.86 | SLC6A4 (0.46) | SLC6A4ADRA2BADRA2ASLC6A2KMT2A | |
| Hydrochloric Acid SCHEMBL5480421 | 0.86 | SLC6A4 (0.46) | SLC6A4ADRA2BADRA2ASLC6A2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070072859-A1 | Pharmaceutical compounds | ELI LILLY AND COMPANY (US) | 2007-03-29 | — | — | US | claimed |
| EP-1725518-A1 | PHARMACEUTICAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2006-11-29 | — | — | EP | claimed |
| WO-2005092835-A1 | PHARMACEUTICAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2005-10-06 | — | — | WO | claimed |
| US-20070072859-A1 | Pharmaceutical compounds | ELI LILLY AND COMPANY (US) | 2007-03-29 | — | — | US | disclosed |
| EP-1725518-A1 | PHARMACEUTICAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2006-11-29 | — | — | EP | disclosed |
| WO-2005092835-A1 | PHARMACEUTICAL COMPOUNDS | ELI LILLY AND COMPANY (US) | 2005-10-06 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070072859-A1 | Pharmaceutical compounds | ADRB3, HTR3C, SLC6A2 | SLC6A4 15/4885ADRA2B 27/4885ADRA2A 40/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.