SCHEMBL5478658

SCHEMBL5478658

CC(=CO[Si](C)(C)C)C(=O)OCCC[SiH3]

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.32
ATM Q13315 1/20 0.32
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3938232 0.82
SCHEMBL22583552 0.81 HCAR2 (0.40) TSHRATMHPGD
SCHEMBL28859093 0.81 TSHR (0.34) TSHRATM
SCHEMBL25222639 0.80
SCHEMBL5175552 0.79
SCHEMBL22974912 0.78 TSHR (0.32) TSHRATMHPGD
SCHEMBL876358 0.78 TSHR (0.37) TSHRATMHPGD
SCHEMBL27823430 0.77 ALDH1A1 (0.39) TSHRATMHPGD
SCHEMBL5784399 0.77 NPSR1 (0.44) TSHR
SCHEMBL28941582 0.77 TSHR (0.32) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 119 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115039021-A Contact lens and manufacturing method thereof 尹景泰 2022-09-09 CN claimed
CN-111714692-B Skin wound surface protection composition and preparation method thereof 华熙生物科技股份有限公司 2022-04-15 CN claimed
CN-108699244-B Silicone monomer, composition for producing silicone hydrogel lens comprising same, and silicone hydrogel lens 茵洛有限公司 2020-12-22 CN claimed
CN-111714692-A Skin wound surface protection composition and preparation method thereof 华熙生物科技股份有限公司 2020-09-29 CN claimed
CN-105037629-A Silicone hydrogel with good resilience and preparation method and application method therefor UNIV SOUTHEAST 2015-11-11 CN claimed
CN-102639636-A Method for increasing ion transmission rate of contact lens NOVARTIS AG 2012-08-15 CN claimed
CN-102246086-A Hydrogel contact lenses KOREA RES INST CHEM TECH 2011-11-16 CN claimed
WO-2001009249-A1 MOISTURE CURABLE ACRYLIC SEALANTS SCHNEE-MOREHEAD, INC. (US) 2001-02-08 WO claimed
EP-0075004-A1 SILICONE METHACRYLATE HYDROGELS FOR CONTACT LENSES McCARRY, John D. (US) 1983-03-30 EP claimed
WO-1982003397-A1 SILICONE METHACRYLATE HYDROGELS FOR CONTACT LENSES MCCARRY JOHN D (US) 1982-10-14 WO claimed
CN-220963396-U Negative electrode and battery 星欧光学股份有限公司 2024-05-14 CN disclosed
CN-114173748-B Polymer film agent having excellent water-repellent and oil-repellent properties at the same time, and cosmetic composition having excellent makeup durability comprising the same 株式会社LG生活健康 2024-03-08 CN disclosed
CN-117199251-A Battery material, negative electrode, battery and battery preparation method 星欧光学股份有限公司 2023-12-08 CN disclosed
CN-116327738-A Patch containing cannabidiol 宝泓生医股份有限公司 2023-06-27 CN disclosed
CN-111253533-B Silicone fluid composition, silicone fluid lens, and method for producing silicone fluid lens 晶硕光学股份有限公司 2023-06-13 CN disclosed
CN-1351631-A Plasma surface treatment of silicone hydrogel contact lenses with a flexible carbon coating BAUSCH & LOMB INCORP (US) 2002-05-29 CN disclosed
CN-1351629-A Surface-treatment of silicone medical devices comprising intermediate carbon coating and graft polymerization BAUSCH & LOMB INCORP (US) 2002-05-29 CN disclosed
CN-1327002-A Surface processed plastic product and surface processing method TORAY INDUSTRIES (JP) 2001-12-19 CN disclosed
EP-0075004-A1 SILICONE METHACRYLATE HYDROGELS FOR CONTACT LENSES McCARRY, John D. (US) 1983-03-30 EP disclosed
WO-1982003397-A1 SILICONE METHACRYLATE HYDROGELS FOR CONTACT LENSES MCCARRY JOHN D (US) 1982-10-14 WO disclosed