Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5393746 | 1.00 | ALDH1A1 (0.41) | ALDH1A1TSHRTHRBGAA | |
| SCHEMBL225859 | 0.97 | — | — | |
| SCHEMBL9181433 | 0.93 | TSHR (0.37) | ALDH1A1TSHRTHRBGAA | |
| SCHEMBL9179902 | 0.88 | TSHR (0.37) | ALDH1A1TSHRTHRBGAA | |
| SCHEMBL6570936 | 0.86 | MEN1 (0.32) | — | |
| SCHEMBL9176884 | 0.85 | ALDH1A1 (0.35) | ALDH1A1TSHR | |
| SCHEMBL5534960 | 0.84 | CYP3A4 (0.33) | TSHRTHRB | |
| SCHEMBL5542838 | 0.84 | — | — | |
| SCHEMBL21634050 | 0.82 | ALDH1A1 (0.39) | ALDH1A1TSHRTHRB | |
| SCHEMBL4182537 | 0.82 | ALDH1A1 (0.36) | ALDH1A1TSHRTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7176234-B2 | Anticancer agents; side effect reduction | CYTOVIA, INC. (US) | 2007-02-13 | — | — | US | claimed |
| EP-1562598-A2 | DERIVATIVES OF GAMBOGIC ACID AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS | Cytovia, Inc. (US) | 2005-08-17 | — | — | EP | claimed |
| US-20040082066-A1 | Derivatives of gambogic acid and analogs as activators of caspases and inducers of apoptosis | CYTOVIA, INC. | 2004-04-29 | — | — | US | claimed |
| WO-2004002428-A2 | DERIVATIVES OF GAMBOGIC ACID AND INDUCE APOPTOSIS | CYTOVIA, INC. (US) | 2004-01-08 | — | — | WO | claimed |
| US-5631354-A | ERYTHROMYCIN DERIVATIVES WITH IMPROVED ANTIBACTERIAL ACTIVITY | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1997-05-20 | — | — | US | claimed |
| US-5523399-A | MACROLIDE ANTIBIOTICS HAVING A STRONG ANTIBACTERIAL ACTIVITY | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1996-06-04 | — | — | US | claimed |
| US-7176234-B2 | Anticancer agents; side effect reduction | CYTOVIA, INC. (US) | 2007-02-13 | — | — | US | disclosed |
| EP-1562598-A2 | DERIVATIVES OF GAMBOGIC ACID AND ANALOGS AS ACTIVATORS OF CASPASES AND INDUCERS OF APOPTOSIS | Cytovia, Inc. (US) | 2005-08-17 | — | — | EP | disclosed |
| US-20040082066-A1 | Derivatives of gambogic acid and analogs as activators of caspases and inducers of apoptosis | CYTOVIA, INC. | 2004-04-29 | — | — | US | disclosed |
| WO-2004002428-A2 | DERIVATIVES OF GAMBOGIC ACID AND INDUCE APOPTOSIS | CYTOVIA, INC. (US) | 2004-01-08 | — | — | WO | disclosed |
| EP-0619320-B1 | 5-O-DESOSAMINYLERYTHRONOLIDE DERIVATIVE | TAISHO PHARMACEUTICAL CO LTD (JP) | 1997-05-21 | — | — | EP | disclosed |
| US-5631354-A | ERYTHROMYCIN DERIVATIVES WITH IMPROVED ANTIBACTERIAL ACTIVITY | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1997-05-20 | — | — | US | disclosed |
| EP-0619319-B1 | 5-0-DESOSAMINYLERYTHRONOLIDE DERIVATIVE | TAISHO PHARMACEUTICAL CO LTD (JP) | 1997-03-05 | — | — | EP | disclosed |
| US-5523399-A | MACROLIDE ANTIBIOTICS HAVING A STRONG ANTIBACTERIAL ACTIVITY | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0501167-B1 | Liquid dye preparations | BASF AG (DE) | 1995-07-05 | — | — | EP | disclosed |
| EP-0619319-A1 | 5-0-DESOSAMINYLERYTHRONOLIDE DERIVATIVE | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1994-10-12 | — | — | EP | disclosed |
| EP-0619320-A1 | 5-O-DESOSAMINYLERYTHRONOLIDE DERIVATIVE | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1994-10-12 | — | — | EP | disclosed |
| US-5205838-A | LIQUID DYE PREPARATIONS: BIS PHENYL-AZO-RESORCINOL IN SOLVENT FOR COLORED RIBBON OR BALL PEN INK | BASF AKTIENGESELLSCHAFT (DE) | 1993-04-27 | — | — | US | disclosed |
| EP-0501167-A1 | Liquid dye preparations | BASF Aktiengesellschaft (DE) | 1992-09-02 | — | — | EP | disclosed |