Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 19/20 | 0.54 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.40 |
| ▸ | KLK7 | P49862 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5467982 | 0.88 | HTR6 (0.53) | HTR6CYP3A4CYP2D6KLK7 | |
| SCHEMBL5408850 | 0.87 | HTR6 (0.57) | HTR6CYP3A4CYP2D6HTR2A | |
| SCHEMBL5334644 | 0.87 | HTR6 (0.59) | HTR6CYP3A4CYP2D6KLK7HTR2A | |
| SCHEMBL5327825 | 0.87 | HTR6 (0.52) | HTR6CYP3A4CYP2D6 | |
| SCHEMBL5465599 | 0.86 | HTR6 (0.58) | HTR6 | |
| SCHEMBL5477723 | 0.81 | HTR6 (0.52) | HTR6CYP3A4CYP2D6KLK7HTR2A | |
| SCHEMBL5333236 | 0.80 | HTR6 (0.54) | HTR6CYP3A4CYP2D6KLK7HTR2A | |
| SCHEMBL3555323 | 0.80 | HTR6 (0.54) | HTR6CYP3A4CYP2D6KLK7HTR2A | |
| SCHEMBL5371262 | 0.78 | HTR6 (0.67) | HTR6 | |
| SCHEMBL948145 | 0.76 | HTR6 (0.69) | HTR6CYP3A4CYP2D6HTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2007020653-A1 | THIOETHER DERIVATIVES AS FUNCTIONAL 5-HT6 LIGANDS | SUVEN LIFE SCIENCES LIMITED (IN) | 2007-02-22 | — | — | WO | disclosed |