Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR2 | P30518 | 5/20 | 0.46 |
| ▸ | AVPR1A | P37288 | 3/20 | 0.38 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.38 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | HRH1 | P35367 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.38 |
| ▸ | GLP1R | P43220 | 1/20 | 0.38 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 2/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 2/20 | 0.36 |
| ▸ | PDK3 | Q15120 | 2/20 | 0.36 |
| ▸ | PDK4 | Q16654 | 2/20 | 0.36 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5496053 | 0.89 | AVPR2 (0.58) | AVPR2AVPR1AABCB11ADRB2HTR1A | |
| SCHEMBL5474822 | 0.86 | MAPT (0.39) | AVPR2AVPR1AABCB11ADRB2HTR1A | |
| SCHEMBL4685307 | 0.80 | AVPR2 (0.45) | AVPR2HRH1L3MBTL1ALDH1A1 | |
| SCHEMBL4680895 | 0.78 | AVPR2 (0.41) | AVPR2AVPR1AABCB11ADRB2HTR1A | |
| SCHEMBL4682848 | 0.77 | AVPR2 (0.45) | AVPR2 | |
| SCHEMBL5486199 | 0.76 | AVPR2 (0.47) | AVPR2AVPR1AABCB11ADRB2HTR1A | |
| SCHEMBL7342308 | 0.71 | MAPT (0.39) | AVPR2AVPR1AABCB11ADRB2HTR1A | |
| SCHEMBL4684984 | 0.70 | AVPR2 (0.49) | AVPR2AVPR1AABCB11ADRB2HTR1A | |
| SCHEMBL4686263 | 0.70 | HTR4 (0.34) | AVPR2PDE2AALDH1A1GAA | |
| SCHEMBL4681210 | 0.70 | MAPT (0.38) | AVPR2AVPR1AABCB11ADRB2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070185323-A1 | Method of preparing benzazepines and derivatives thereof | ECOLE POLYTECHNIQUE (FR) | 2007-08-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070185323-A1 | Method of preparing benzazepines and derivatives thereof | CYP2F1, MAOB, CYP1A2 | AVPR2 1203/4885AVPR1A 2001/4885ABCB11 3034/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.