SCHEMBL5481100

SCHEMBL5481100

O=C(O)N1C(=O)C=C(N2C(=O)CCC2=O)C1=O

nearest known ligand 0.38

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CA12 O43570 2/20 0.38
CA1 P00915 2/20 0.38
CA9 Q16790 2/20 0.38
KMT2A Q03164 1/20 0.31
GLA P06280 1/20 0.31
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19583420 0.71 CA12 (0.32) CA12CA1CA9CA2
SCHEMBL15741868 0.70 CA12 (0.68) CA12CA1CA9KMT2ACA2
SCHEMBL6037886 0.69 GLA (0.41) CA12CA1CA9KMT2AGLA
SCHEMBL317539 0.67 CA12 (0.38) CA12CA1CA9
SCHEMBL9435785 0.66 BACE1 (0.36) KMT2A
Hydrochloric Acid SCHEMBL28361628 0.65 CA12 (0.37) CA12CA1CA9
Ethylene Glycol SCHEMBL29111203 0.65 CA12 (0.33) CA12CA1CA9
Acetic Acid SCHEMBL4526901 0.64 CA12 (0.36) CA12CA1CA9KMT2AGLA
Succinimide SCHEMBL19834291 0.61 CRBN (0.50) CA12CA1CA9
Propionic Acid SCHEMBL12804227 0.61 CA12 (0.33) CA12CA1CA9KMT2AGLA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070148702-A1 MEASURING CHIP FOR SURFACE PLASMON RESONANCE BIOSENSOR AND METHOD FOR PRODUCING THE SAME Karube, Isao (JP) 2007-06-28 US claimed
US-20030224441-A1 Measuring chip for surface plasmon resonance biosensor and method for producing the same DAI NIPPON PRINTING CO., LTD. (JP) 2003-12-04 US claimed
US-6627397-B1 Comprising thin gold film, plasma polymerization layers, immobilized biologically active substances; use for detection of small amount of target substances in high sensitivity DAI NIPPON PRINTING CO., LTD. (JP) 2003-09-30 US claimed
US-20070148702-A1 MEASURING CHIP FOR SURFACE PLASMON RESONANCE BIOSENSOR AND METHOD FOR PRODUCING THE SAME Karube, Isao (JP) 2007-06-28 US disclosed
EP-0945721-B1 Biosensitive element for surface plasmon resonance measurements, and its method of manufacture DAINIPPON PRINTING CO LTD (JP) 2004-11-17 EP disclosed
US-20030224441-A1 Measuring chip for surface plasmon resonance biosensor and method for producing the same DAI NIPPON PRINTING CO., LTD. (JP) 2003-12-04 US disclosed
US-6627397-B1 Comprising thin gold film, plasma polymerization layers, immobilized biologically active substances; use for detection of small amount of target substances in high sensitivity DAI NIPPON PRINTING CO., LTD. (JP) 2003-09-30 US disclosed
US-6183971-B1 NEUTRALIZING MONOCLONAL ANTIBODY WHICH BINDS TO CELL GROWTH FACTOR OF DEFINED AMINO ACID SEQUENCE; DIAGNOSIS OF DIABETES AND COMPLICATIONS; THERAPY OF ARTERIOSCLEROSIS AND CANCER; ANTICARCINOGENIC AGENTS; FOR PURIFICATION OF BETACELLULIN TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 2001-02-06 US disclosed
EP-0945721-A2 Biosensitive element for surface plasmon resonance measurements, and its method of manufacture DAI NIPPON PRINTING CO., LTD. (JP) 1999-09-29 EP disclosed
US-5712100-A Antibodies to peptides having NGF-like activity, and use thereof TAKEDA LIMITED INDUSTRIES, LTD. (JP) 1998-01-27 US disclosed
EP-0817842-A1 ANTIBODY TO HUMAN BETACELLULIN AND USE THEREOF Takeda Chemical Industries, Ltd. (JP) 1998-01-14 EP disclosed
EP-0418590-B1 Antibodies, production thereof and use TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1997-11-19 EP disclosed
US-5656435-A GENETIC ENGINEERING; DETECTION, ANALYZING A POLYPEPTIDES TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1997-08-12 US disclosed
US-5571895-A GLIA ACTIVATING FACTOR TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1996-11-05 US disclosed
WO-1996030506-A1 ANTIBODY TO HUMAN BETACELLULIN AND USE THEREOF TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1996-10-03 WO disclosed
US-5437995-A Recognizes human acidic fibroblast growth factor protein; binding affinity not inhibited by heparin TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1995-08-01 US disclosed
EP-0608546-A2 Glia activating factor (GAF), antibodies against it and their uses TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1994-08-03 EP disclosed
EP-0507948-A1 MONOCLONAL ANTIBODY, HYBRIDOMAS, THEIR PRODUCTION AND USE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1992-10-14 EP disclosed
WO-1991009875-A1 MONOCLONAL ANTIBODY, HYBRIDOMAS, THEIR PRODUCTION AND USE TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) 1991-07-11 WO disclosed
EP-0420081-A1 Monoclonal antibody against an acidic FGF protein, its production and use Takeda Chemical Industries, Ltd. (JP) 1991-04-03 EP disclosed