Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8604768 | 0.89 | CA12 (0.33) | CA12CA1CA9 | |
| SCHEMBL9723881 | 0.67 | MGLL (0.37) | — | |
| SCHEMBL6037886 | 0.63 | GLA (0.41) | CA12CA1CA9GLAKMT2A | |
| Acetic Acid SCHEMBL3486649 | 0.62 | FFAR3 (0.35) | CA12CA1CA9GLAKMT2A | |
| Acetic Acid SCHEMBL482738 | 0.61 | FFAR3 (0.39) | CA12CA1CA9GLAKMT2A | |
| Acetic Acid SCHEMBL21834859 | 0.61 | FFAR3 (0.39) | CA12CA1CA9GLAKMT2A | |
| SCHEMBL5669047 | 0.61 | MGLL (0.32) | — | |
| Acetic Acid SCHEMBL3939404 | 0.60 | FFAR3 (0.37) | CA12CA1CA9GLAKMT2A | |
| Succinchlorimide SCHEMBL27913334 | 0.60 | FFAR3 (0.37) | CA12CA1CA9GLAKMT2A | |
| SCHEMBL1425299 | 0.59 | PTGS2 (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113087650-A | Preparation method of 2-maleimidoacetic acid N-hydroxysuccinimide ester | 苏州昊帆生物股份有限公司 | 2021-07-09 | — | — | CN | disclosed |
| WO-2021085526-A1 | BIOCHIP AND DETECTION METHOD | 東レ株式会社 | 2021-05-06 | — | — | WO | disclosed |
| US-20190285576-A1 | SEMICONDUCTOR SENSOR, METHOD FOR PRODUCING THE SAME, AND COMBINED SENSOR | TORAY INDUSTRIES, INC. (JP) | 2019-09-19 | — | — | US | disclosed |
| EP-3531131-A1 | SEMICONDUCTOR SENSOR AND MANUFACTURING METHOD FOR SAME, AND COMPOUND SENSOR | Toray Industries, Inc. (JP) | 2019-08-28 | — | — | EP | disclosed |
| US-20090233280-A1 | METHOD OF ACQUIRING INFORMATION REGARDING BASE SEQUENCE AND INFORMATION READING DEVICE FOR THE SAME | CANON KABUSHIKI KAISHA (JP) | 2009-09-17 | — | — | US | disclosed |
| WO-2007077952-A1 | METHOD AND DEVICE FOR DETERMINING A NUCLEIC ACID ALLELE OR BASE SEQUENCE | CANON KABUSHIKI KAISHA (JP) | 2007-07-12 | — | — | WO | disclosed |