SCHEMBL5481146

SCHEMBL5481146

CCNS(=O)(=O)CC(C)N

nearest known ligand 0.34

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TP53 P04637 1/20 0.34
GRIA1 P42261 3/20 0.33
GBA1 P04062 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12988561 0.80 GRIA1 (0.41) GRIA1
SCHEMBL21603671 0.79 ALDH1A1 (0.35) GRIA1GBA1
SCHEMBL19136509 0.74
SCHEMBL19136507 0.74
SCHEMBL18611380 0.73 TSHR (0.36) GRIA1
SCHEMBL779252 0.70
SCHEMBL13458019 0.69
SCHEMBL777408 0.69
SCHEMBL2882818 0.69
SCHEMBL15673083 0.68 CA1 (0.36) GRIA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1310882-C Sulfonamide derivatives, insecticides for agricultural and horticultural use, and usage thereof NIHON NOHYAKU CO LTD (JP) 2007-04-18 CN disclosed
US-7161032-B2 Sulfonamide derivatives, insecticides for agricultural and horticultural use, and usage thereof NIHON NOHYAKU CO., LTD. (JP) 2007-01-09 US disclosed
US-20060167315-A1 Sulfonamide derivatives, insecticides for agricultural and horticultural use, and usage thereof NIHON NOHYAKU CO., LTD. (JP) 2006-07-27 US disclosed
CN-1692098-A Sulfonamide derivatives, insecticides for agricultural and horticultural use, and usage thereof NIHON NOHYAKU CO LTD (JP) 2005-11-02 CN disclosed
EP-1544193-A1 SULFONAMIDE DERIVATIVES, INSECTICIDES FOR AGRICULTURAL AND HORTICULTURAL USE, AND USAGE THEREOF Nihon Nohyaku Co., Ltd. (JP) 2005-06-22 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060167315-A1 Sulfonamide derivatives, insecticides for agricultural and horticultural use, and usage thereof CBR3, CNPY2, STS TP53 4685/4885GRIA1 2810/4885GBA1 565/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.