SCHEMBL5481206

SCHEMBL5481206

CCOC(=O)C(C)(C)Oc1c(C)cc(CNCc2ncc(C)o2)cc1C

nearest known ligand 0.35

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
PPARA Q07869 15/20 0.35
PPARG P37231 10/20 0.35
ABCB11 O95342 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP3A4 P08684 1/20 0.35
TSHR P16473 1/20 0.35
HTR2A P28223 1/20 0.35
PMP22 Q01453 1/20 0.35
PPARD Q03181 8/20 0.34
PDE10A Q9Y233 1/20 0.33
FBP1 P09467 1/20 0.32
LMNA P02545 1/20 0.32
POLB P06746 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5479672 0.84 PPARA (0.36) PPARAPPARGABCB11CYP1A2CYP3A4
SCHEMBL14414924 0.84 PPARA (0.36) PPARAPPARGABCB11CYP1A2CYP3A4
SCHEMBL5484195 0.81 PPARA (0.37) PPARAPPARGABCB11CYP1A2CYP3A4
SCHEMBL5480744 0.77 ALDH1A1 (0.38) PPARAPPARGABCB11CYP1A2CYP3A4
SCHEMBL5472027 0.77 PPARA (0.35) PPARAPPARGABCB11CYP1A2CYP3A4
SCHEMBL5484176 0.75 PPARA (0.44) PPARAPPARGCYP1A2PPARD
SCHEMBL5477521 0.74 PPARA (0.39) PPARAPPARGABCB11CYP1A2CYP3A4
SCHEMBL21016866 0.74 PPARA (0.47) PPARAPPARGABCB11CYP1A2CYP3A4
SCHEMBL5480241 0.74 PPARA (0.44) PPARAPPARGCYP1A2PPARDLMNA
SCHEMBL14414920 0.73 PPARA (0.62) PPARAPPARGPPARD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070208021-A1 Phenoxyacetic Acid Derivatives and Drug Comprising The Same DAIICHI PHARMACEUTICAL CO., LTD. 2007-09-06 US disclosed
US-20070208021-A1 Phenoxyacetic Acid Derivatives and Drug Comprising The Same DAIICHI PHARMACEUTICAL CO., LTD. 2007-09-06 US disclosed
US-20070208021-A1 Phenoxyacetic Acid Derivatives and Drug Comprising The Same DAIICHI PHARMACEUTICAL CO., LTD. 2007-09-06 US disclosed
EP-1731513-A1 PHENOXYACETIC ACID DERIVATIVE AND MEDICINE CONTAINING THE SAME DAIICHI PHARMACEUTICAL CO., LTD. (JP) 2006-12-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070208021-A1 Phenoxyacetic Acid Derivatives and Drug Comprising The Same PPARA, PPARG, PPARD PPARA 1/4885PPARG 2/4885ABCB11 798/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.