Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 2/20 | 0.52 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.39 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | IDH1 | O75874 | 3/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.37 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | PTGDR | Q13258 | 1/20 | 0.37 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.37 |
| ▸ | LIPE | Q05469 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5481305 | 1.00 | PPARD (0.52) | PPARDPTGDR2HSD11B1CHRM2CHRM1 | |
| SCHEMBL14431186 | 0.91 | PPARD (0.51) | PPARDPTGDR2HSD11B1CHRM2CHRM1 | |
| SCHEMBL5471264 | 0.91 | PPARD (0.51) | PPARDPTGDR2HSD11B1CHRM2CHRM1 | |
| SCHEMBL5746202 | 0.91 | PPARD (0.52) | PPARDPTGDR2HSD11B1CHRM2CHRM1 | |
| SCHEMBL6348336 | 0.88 | HSD11B1 (0.53) | PPARDPTGDR2HSD11B1CHRM2CHRM1 | |
| SCHEMBL5776063 | 0.88 | PPARD (0.50) | PPARDPTGDR2HSD11B1CHRM2CHRM1 | |
| SCHEMBL6348338 | 0.88 | HSD11B1 (0.53) | PPARDPTGDR2HSD11B1CHRM2CHRM1 | |
| SCHEMBL4212887 | 0.87 | PTGDR2 (0.42) | PPARDPTGDR2CHRM2CHRM1CHRM5 | |
| SCHEMBL13804972 | 0.87 | PTGDR2 (0.42) | PPARDPTGDR2CHRM2CHRM1CHRM5 | |
| SCHEMBL13805070 | 0.86 | PTGDR2 (0.40) | PPARDPTGDR2HSD11B1IDH1PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070190079-A1 | METHODS FOR THE SELECTIVE MODULATION OF PPAR | KALYPSYS, INC. (US) | 2007-08-16 | — | — | US | disclosed |
| US-20070190079-A1 | METHODS FOR THE SELECTIVE MODULATION OF PPAR | KALYPSYS, INC. (US) | 2007-08-16 | — | — | US | disclosed |
| US-20070190079-A1 | METHODS FOR THE SELECTIVE MODULATION OF PPAR | KALYPSYS, INC. (US) | 2007-08-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070190079-A1 | METHODS FOR THE SELECTIVE MODULATION OF PPAR | PPARG, PPARA, PPARD | PPARD 3/4885PTGDR2 427/4885HSD11B1 332/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.