Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Adipic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 5/20 | 0.61 |
| ▸ | FFAR1 | O14842 | 3/20 | 0.61 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.61 |
| ▸ | CAMK2A | Q9UQM7 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | GSTK1 | Q9Y2Q3 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 6/20 | 0.43 |
| ▸ | PPARD | Q03181 | 6/20 | 0.43 |
| ▸ | PPARA | Q07869 | 6/20 | 0.43 |
| ▸ | HDAC11 | Q96DB2 | 5/20 | 0.43 |
| ▸ | TLR2 | O60603 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
| ▸ | FABP4 | P15090 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.43 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.43 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Adipic Acid SCHEMBL28427724 | 1.00 | GPR84 (0.61) | GPR84FFAR1FFAR4CAMK2ATSHR | |
| Sebacic Acid SCHEMBL5476770 | 1.00 | GPR84 (0.61) | GPR84FFAR1FFAR4CAMK2ATSHR | |
| Azelaic Acid SCHEMBL5485119 | 1.00 | GPR84 (0.61) | GPR84FFAR1FFAR4CAMK2ATSHR | |
| Pimelic Acid SCHEMBL30288573 | 0.94 | GPR84 (0.58) | GPR84FFAR1FFAR4CAMK2ATSHR | |
| SCHEMBL10930379 | 0.94 | TSHR (0.52) | GPR84FFAR1FFAR4TSHRLMNA | |
| SCHEMBL8984369 | 0.94 | TSHR (0.52) | GPR84FFAR1FFAR4TSHRLMNA | |
| SCHEMBL8984506 | 0.94 | TSHR (0.52) | GPR84FFAR1FFAR4TSHRLMNA | |
| SCHEMBL8984439 | 0.94 | TSHR (0.52) | GPR84FFAR1FFAR4TSHRLMNA | |
| SCHEMBL8984358 | 0.92 | GPR84 (0.67) | GPR84FFAR1FFAR4CAMK2ATSHR | |
| SCHEMBL8984604 | 0.92 | GPR84 (0.67) | GPR84FFAR1FFAR4CAMK2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113226642-A | Polishing pad | 株式会社可乐丽 | 2021-08-06 | — | — | CN | claimed |
| CN-118019616-A | Polishing pad | 株式会社可乐丽 | 2024-05-10 | — | — | CN | disclosed |
| CN-117980109-A | Polishing pad | 株式会社可乐丽 | 2024-05-03 | — | — | CN | disclosed |
| CN-113226642-A | Polishing pad | 株式会社可乐丽 | 2021-08-06 | — | — | CN | disclosed |
| US-20070277650-A1 | Cleaning blade member | SYNZTEC CO., LTD. (JP) | 2007-12-06 | — | — | US | disclosed |
| US-6600003-B2 | Rebound resilience; for parts such as a cleaning part, a charge-imparting part, a development part, an image-transfer part, or a paper-feed part | HOKUSHIN CORPORATION (JP) | 2003-07-29 | — | — | US | disclosed |
| US-20020037990-A1 | Rubber member for use in electrophotographic apparatus and rubber member for separating paper sheets | SYNZTEC CO., LTD. (JP) | 2002-03-28 | — | — | US | disclosed |
| EP-1180731-A2 | Rubber member for use in electrophotographic apparatus and rubber member for separating paper sheets | HOKUSHIN CORPORATION (JP) | 2002-02-20 | — | — | EP | disclosed |