Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.45 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30519851 | 0.81 | CYP3A4 (0.50) | CYP3A4TRPA1ALDH1A1TDP1HPGD | |
| SCHEMBL645833 | 0.81 | CYP3A4 (0.50) | CYP3A4TRPA1ALDH1A1TDP1HPGD | |
| SCHEMBL29123916 | 0.80 | APLNR (0.36) | CYP3A4ALDH1A1TDP1HPGDCYP1A2 | |
| SCHEMBL31115173 | 0.79 | CYP3A4 (0.52) | CYP3A4TRPA1ALDH1A1TDP1HPGD | |
| SCHEMBL627870 | 0.79 | CYP3A4 (0.52) | CYP3A4TRPA1ALDH1A1TDP1HPGD | |
| SCHEMBL608937 | 0.79 | CYP3A4 (0.48) | CYP3A4TRPA1ALDH1A1TDP1HPGD | |
| SCHEMBL31115174 | 0.79 | CYP3A4 (0.52) | CYP3A4TRPA1ALDH1A1TDP1HPGD | |
| SCHEMBL27900891 | 0.78 | CYP3A4 (0.47) | CYP3A4TRPA1ALDH1A1TDP1HPGD | |
| SCHEMBL3841180 | 0.76 | CYP3A4 (0.45) | CYP3A4TRPA1ALDH1A1TDP1HPGD | |
| SCHEMBL11667358 | 0.76 | CYP3A4 (0.48) | CYP3A4TRPA1ALDH1A1TDP1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114040934-A | Polymerizable composition for producing polyisocyanurate-based plastics having extended pot life | 科思创知识产权两合公司 | 2022-02-11 | — | — | CN | disclosed |
| EP-2246333-B1 | Indazole, benzisoxazole, and benzisothiazole kinase inhibitors | ABBOTT LAB (US) | 2012-10-24 | — | — | EP | disclosed |
| US-20070135387-A1 | Inhibitors of protein kinases | ABBOTT LABORATORIES | 2007-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070135387-A1 | Inhibitors of protein kinases | MAP3K20, PACSIN2, MAP4K2 | CYP3A4 4628/4885TRPA1 4486/4885ALDH1A1 4438/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.