Benzylamine

Benzylamine

SCHEMBL5481672

NCc1ccccc1.NCc1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LOXL2 Q9Y4K0 5/20 1.00
TAAR1 Q96RJ0 4/20 0.68
CYP2A6 P11509 2/20 0.58
HTR2A P28223 1/20 0.58
SMN1; SMN2 Q16637 1/20 0.58
MAOB P27338 1/20 0.56
CYP1A2 P05177 1/20 0.56
CYP2D6 P10635 1/20 0.56
CYP2C9 P11712 1/20 0.56
TSHR P16473 1/20 0.56
CYP2C19 P33261 1/20 0.56
HRH3 Q9Y5N1 1/20 0.56
PNMT P11086 1/20 0.55
ENPP2 Q13822 1/20 0.55
CALM1 P0DP23 1/20 0.53
MAOA P21397 2/20 0.50
SLC6A2 P23975 2/20 0.50
SLC6A4 P31645 1/20 0.50
SLC6A3 Q01959 1/20 0.50
ABAT P80404 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzylamine SCHEMBL1331207 1.00
Benzylamine SCHEMBL10707644 1.00 LOXL2 (1.00) LOXL2TAAR1CYP2A6HTR2ASMN1; SMN2
SCHEMBL19242392 1.00 LOXL2 (1.00) LOXL2TAAR1CYP2A6HTR2ASMN1; SMN2
Benzylamine SCHEMBL373 1.00
Benzylamine SCHEMBL23044734 0.97 LOXL2 (0.93) LOXL2TAAR1CYP2A6HTR2ASMN1; SMN2
Benzylamine SCHEMBL4306051 0.97
Benzylamine SCHEMBL1245462 0.97
Benzylamine SCHEMBL20357787 0.97
Benzylamine SCHEMBL8751247 0.97
Benzylamine SCHEMBL10738289 0.97 LOXL2 (0.93) LOXL2TAAR1CYP2A6HTR2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119136633-A Enhanced perovskite materials for photovoltaic devices 立方光伏股份有限公司 2024-12-13 CN disclosed
CN-113272311-B Enhanced perovskite materials for photovoltaic devices 亨特钙钛矿技术有限责任公司 2024-09-10 CN disclosed
CN-115152037-A 2D perovskite tandem photovoltaic device 立方光伏股份有限公司 2022-10-04 CN disclosed
CN-112409205-B Application of carbon nanocages in catalyzing aromatic imino compounds to perform oxidative coupling reaction 南京大学 2021-12-17 CN disclosed
CN-112409205-A Application of carbon nanocages in catalyzing aromatic imino compounds to perform oxidative coupling reaction 南京大学 2021-02-26 CN disclosed
CN-103102303-B As the benzyl amine derivative of CETP inhibitor DR. REDDY'S LABORATORIES LTD. (IN) 2015-10-28 CN disclosed
CN-203816467-U Environment-friendly soluble waste gas component purification device specially used for macromolecule enterprise CHEN PENG 2014-09-10 CN disclosed
CN-103920370-A Environment-friendly waste gas purification device and waste gas treatment method specially for high polymer enterprises CHEN PENG 2014-07-16 CN disclosed
CN-103102303-A Benzylamine derivatives as CETP inhibitors REDDY US THERAPEUTICS INC 2013-05-15 CN disclosed
CN-101443006-B Novel benzylamine derivatives as CETP inhibitors REDDY US THERAPEUTICS INC 2012-10-10 CN disclosed
CN-101443006-A Novel benzylamine derivatives as CETP inhibitors REDDY US THERAPEUTICS INC (US) 2009-05-27 CN disclosed
US-20070059230-A1 Process GLAXO GROUP LIMITED 2007-03-15 US disclosed
EP-1663868-A2 PROCESS FOR PREPARING RADIOLABELLED COMPOUNDS GLAXO GROUP LIMITED (GB) 2006-06-07 EP disclosed
CN-1218929-C Method for preparing benzyl amine by catalytic hydrogenation CHINA PETROLEUM & CHEMICAL (CN) 2005-09-14 CN disclosed
WO-2005014479-A2 PROCESS FOR PREPARING RADIOLABELED COMPOUNDS GLAXO GROUP LIMITED (GB) 2005-02-17 WO disclosed
CN-1021825-C Preparation method of aromatic W-alkylimino-tetrahydro-6H-1, 3-thiazine-6-one derivative MERRELL DOW PHARMA (US) 1993-08-18 CN disclosed
CN-87101690-A Preparation and application of aromatic omega-alkylimino-tetrahydro-6H-1, 3-thiazine-6-one derivative 1987-12-30 CN disclosed
US-4671890-A CURING AGENT FOR THERMOSETTING RESINS MITSUI TOATSU CHEMICALS, INC. (JP) 1987-06-09 US disclosed