Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 18/20 | 0.46 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.46 |
| ▸ | PPARA | Q07869 | 7/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5691785 | 0.92 | HTR6 (0.41) | PPARDFFAR1 | |
| SCHEMBL14508397 | 0.82 | PPARD (0.40) | PPARD | |
| SCHEMBL12749616 | 0.82 | PPARD (0.46) | PPARDFFAR1PPARA | |
| SCHEMBL3411465 | 0.79 | ESR1 (0.62) | PPARDFFAR1PPARAESR1ESR2 | |
| SCHEMBL28601267 | 0.77 | FFAR1 (0.50) | PPARDFFAR1PPARAESR1ESR2 | |
| SCHEMBL28601201 | 0.77 | FFAR1 (0.50) | PPARDFFAR1PPARAESR1ESR2 | |
| SCHEMBL14508402 | 0.75 | CYP11B1 (0.43) | — | |
| SCHEMBL10444045 | 0.75 | FFAR1 (0.47) | PPARDFFAR1PPARA | |
| SCHEMBL1472802 | 0.74 | PPARD (0.46) | PPARDFFAR1PPARA | |
| SCHEMBL8037012 | 0.73 | PPARD (0.48) | PPARDFFAR1PPARAESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070117860-A1 | Bicyclic indolinesulphonamide derivatives | BAYER HEALTHCARE AG (DE) | 2007-05-24 | — | — | US | disclosed |
| EP-1654227-A1 | BICYCLIC INDOLINE SULFONAMIDE DERIVATIVES | Bayer HealthCare AG (DE) | 2006-05-10 | — | — | EP | disclosed |
| WO-2005016881-A1 | BICYCLIC INDOLINE SULFONAMIDE DERIVATIVES | BAYER HEALTHCARE AG (DE) | 2005-02-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070117860-A1 | Bicyclic indolinesulphonamide derivatives | PPARD, PPARA, PPARG | PPARD 1/4885FFAR1 21/4885PPARA 2/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.