Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRKCI | P41743 | 1/20 | 0.55 |
| ▸ | MTOR | P42345 | 1/20 | 0.53 |
| ▸ | ADK | P55263 | 1/20 | 0.53 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.53 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.53 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.53 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.52 |
| ▸ | CCND1 | P24385 | 1/20 | 0.52 |
| ▸ | CCNC | P24863 | 1/20 | 0.52 |
| ▸ | CDK8 | P49336 | 1/20 | 0.52 |
| ▸ | CDK7 | P50613 | 1/20 | 0.52 |
| ▸ | CDK9 | P50750 | 1/20 | 0.52 |
| ▸ | CCNH | P51946 | 1/20 | 0.52 |
| ▸ | MNAT1 | P51948 | 1/20 | 0.52 |
| ▸ | CDK6 | Q00534 | 1/20 | 0.52 |
| ▸ | PARP1 | P09874 | 4/20 | 0.51 |
| ▸ | VCP | P55072 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45099 | 0.85 | KDM4E (0.68) | MTORADKNISCHKDM4EALDH1A1 | |
| SCHEMBL29569789 | 0.85 | KDM4E (0.68) | MTORADKNISCHKDM4EALDH1A1 | |
| SCHEMBL12647965 | 0.84 | NISCH (0.53) | MTORADKNISCHKDM4EALDH1A1 | |
| SCHEMBL6843665 | 0.82 | MAP2K4 (0.62) | PRKCIKDM4EALDH1A1PARP1MAP2K4 | |
| SCHEMBL3634334 | 0.81 | KDM4E (0.72) | MTORADKNISCHKDM4EALDH1A1 | |
| SCHEMBL3062520 | 0.81 | KDM4E (0.70) | MTORADKNISCHKDM4EALDH1A1 | |
| SCHEMBL16777437 | 0.80 | NISCH (0.72) | MTORADKNISCHKDM4EALDH1A1 | |
| SCHEMBL12664163 | 0.80 | KDM4E (0.49) | MTORADKNISCHKDM4EALDH1A1 | |
| SCHEMBL6610117 | 0.79 | VCP (0.53) | MTORADKNISCHKDM4EALDH1A1 | |
| SCHEMBL4631461 | 0.78 | PRKCI (0.54) | PRKCICCNT1CCND1CCNCCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1819341-A2 | IL-12 MODULATORY COMPOUNDS | Synta Pharmaceuticals Corporation (US) | 2007-08-22 | — | — | EP | claimed |
| WO-2006053227-A2 | IL-12 MODULATORY COMPOUNDS | SYNTA PHARMACEUTICALS CORP. (US) | 2006-05-18 | — | — | WO | claimed |