Tryptophan

Tryptophan

SCHEMBL5481922

CC(O)[C@H](N)C(=O)O.N[C@@H](Cc1c[nH]c2ccccc12)C(=O)O

nearest known ligand 0.80

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 3/20 0.80
▸ MAPT P10636 3/20 0.80
▸ KMT2A Q03164 3/20 0.80
▸ LMNA P02545 2/20 0.80
▸ TSHR P16473 2/20 0.80
▸ BLM P54132 2/20 0.80
▸ PMP22 Q01453 2/20 0.80
▸ MEN1 O00255 2/20 0.80
▸ MPO P05164 1/20 0.80
▸ HIF1A Q16665 1/20 0.80
▸ APAF1 O14727 1/20 0.64
▸ POLB P06746 1/20 0.64
▸ RECQL P46063 1/20 0.64
▸ L3MBTL1 Q9Y468 1/20 0.64
▸ SMN1; SMN2 Q16637 1/20 0.61
▸ HTR2A P28223 3/20 0.58
▸ HTR1A P08908 2/20 0.58
▸ HTR2C P28335 2/20 0.58
▸ SLC6A4 P31645 2/20 0.58
▸ HTR7 P34969 2/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Tryptophan SCHEMBL11217425 1.00 KDM4E (0.80) KDM4EMAPTKMT2ALMNATSHR
Dl-Tryptophan SCHEMBL12497478 1.00 KDM4E (0.80) KDM4EMAPTKMT2ALMNATSHR
Dl-Tryptophan SCHEMBL27147785 1.00 KDM4E (0.80) KDM4EMAPTKMT2ALMNATSHR
Tryptophan SCHEMBL6268677 1.00 KDM4E (0.80) KDM4EMAPTKMT2ALMNATSHR
Dl-Tryptophan SCHEMBL537138 1.00 KDM4E (0.80) KDM4EMAPTKMT2ALMNATSHR
Tryptophan SCHEMBL12497474 1.00 KDM4E (0.80) KDM4EMAPTKMT2ALMNATSHR
Tryptophan SCHEMBL537140 1.00 KDM4E (0.80) KDM4EMAPTKMT2ALMNATSHR
Dl-Tryptophan SCHEMBL28120361 0.98 KDM4E (0.76) KDM4EMAPTKMT2ALMNATSHR
Tryptophan SCHEMBL7154073 0.96 KDM4E (0.74) KDM4EMAPTKMT2ALMNATSHR
Dl-Tryptophan SCHEMBL7859113 0.96 KDM4E (0.74) KDM4EMAPTKMT2ALMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117279506-A Tumor storage and cell culture compositions 艾欧凡斯生物治疗公司 2023-12-22 — — CN disclosed
US-20150301067-A1 METHODS AND ASSAYS FOR FACIOSCAPULOHUMERAL MUSCULAR DYSTROPHY UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) 2015-10-22 — — US disclosed
WO-2014071340-A1 METHODS AND ASSAYS FOR FACIOSCAPULOHUMERAL MUSCULAR DYSTROPHY UNIVERSITY OF WASHINGTON THROUGH ITS CENTER FOR COMMERCIALIZATION (US) 2014-05-08 — — WO disclosed
US-20070141681-A1 Process for the production of L-amino acids using strains of the Enterobacteriaceae family DEGUSSA AG (DE) 2007-06-21 — — US disclosed
US-7211415-B2 Enterobacteriaceae strains over-expressing the yfiD gene for the fermentative production of L-amino acids DEGUSSA AG (DE) 2007-05-01 — — US disclosed
US-20040235122-A1 Process for the production of L-amino acids using strains of the enterobacteriaceae family EVONIK OPERATIONS GMBH (DE) 2004-11-25 — — US disclosed
US-4211795-A Animal feeds Institut National de la Recherche Agronomique and Aussedat-Rey (FR) 1980-07-08 — — US disclosed
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