Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.80 |
| ▸ | MAPT | P10636 | 3/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.80 |
| ▸ | LMNA | P02545 | 2/20 | 0.80 |
| ▸ | TSHR | P16473 | 2/20 | 0.80 |
| ▸ | BLM | P54132 | 2/20 | 0.80 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.80 |
| ▸ | MEN1 | O00255 | 2/20 | 0.80 |
| ▸ | MPO | P05164 | 1/20 | 0.80 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.80 |
| ▸ | APAF1 | O14727 | 1/20 | 0.64 |
| ▸ | POLB | P06746 | 1/20 | 0.64 |
| ▸ | RECQL | P46063 | 1/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.61 |
| ▸ | HTR2A | P28223 | 3/20 | 0.58 |
| ▸ | HTR1A | P08908 | 2/20 | 0.58 |
| ▸ | HTR2C | P28335 | 2/20 | 0.58 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.58 |
| ▸ | HTR7 | P34969 | 2/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Tryptophan SCHEMBL6268677 | 1.00 | KDM4E (0.80) | KDM4EMAPTKMT2ALMNATSHR | |
| Tryptophan SCHEMBL537140 | 1.00 | KDM4E (0.80) | KDM4EMAPTKMT2ALMNATSHR | |
| Dl-Tryptophan SCHEMBL27147785 | 1.00 | KDM4E (0.80) | KDM4EMAPTKMT2ALMNATSHR | |
| Dl-Tryptophan SCHEMBL12497478 | 1.00 | KDM4E (0.80) | KDM4EMAPTKMT2ALMNATSHR | |
| Tryptophan SCHEMBL12497474 | 1.00 | KDM4E (0.80) | KDM4EMAPTKMT2ALMNATSHR | |
| Tryptophan SCHEMBL11217425 | 1.00 | KDM4E (0.80) | KDM4EMAPTKMT2ALMNATSHR | |
| Tryptophan SCHEMBL5481922 | 1.00 | KDM4E (0.80) | KDM4EMAPTKMT2ALMNATSHR | |
| Dl-Tryptophan SCHEMBL28120361 | 0.98 | KDM4E (0.76) | KDM4EMAPTKMT2ALMNATSHR | |
| Tryptophan SCHEMBL7154073 | 0.96 | KDM4E (0.74) | KDM4EMAPTKMT2ALMNATSHR | |
| Dl-Tryptophan SCHEMBL7859113 | 0.96 | KDM4E (0.74) | KDM4EMAPTKMT2ALMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8383840-B1 | Extraction of fulvic minerals, vitamins, amino acids, enzymes, and phytonutrients from humic substances | MCMAHON GEOFF (US) | 2013-02-26 | — | — | US | claimed |
| CN-117715632-A | Compositions comprising an enzyme-cleavable prodrug and nafamostat and methods of use thereof | 恩赛斯生物科学股份有限公司 | 2024-03-15 | — | — | CN | disclosed |
| WO-2020081525-A1 | ELECTROMAGNETIC AND FREQUENCY ENHANCED AGRICULTURE | SONIPHI LLC (US) | 2020-04-23 | — | — | WO | disclosed |
| CN-109689085-A | COMPOSITIONS AND METHODS FOR TREATING PULMONARY HYPERTENSION | 阿塞勒隆制药公司 | 2019-04-26 | — | — | CN | disclosed |
| CN-107847561-A | TGF- β superfamily type I and type II receptor heteromultimers and uses thereof | 阿塞勒隆制药公司 | 2018-03-27 | — | — | CN | disclosed |
| CN-104662154-B | Use the manufacture method of the lipid of thioesterase variant | 花王株式会社 | 2017-09-01 | — | — | CN | disclosed |
| US-20170042209-A1 | COMPOSITION COMPRISING SACHA INCHI PROTEIN IN COMBINATION WITH OTHER PLANT PROTEINS | SHAKLEE CORPORATION | 2017-02-16 | — | — | US | disclosed |
| WO-2017027599-A1 | COMPOSITION COMPRISING SACHA INCHI PROTEIN IN COMBINATION WITH OTHER PLANT PROTEINS | SHAKLEE CORPORATION (US) | 2017-02-16 | — | — | WO | disclosed |
| CN-103517987-B | Change type lipase and manufacture method thereof and use the reaction of this enzyme | 宇部兴产株式会社 | 2016-10-12 | — | — | CN | disclosed |
| CN-103539831-B | Ansu apricot alpha-glucosaccharase enzyme inhibition peptide and its production and use | BEIJING FORESTRY UNIVERSITY (CN) | 2016-02-03 | — | — | CN | disclosed |
| CN-101129165-B | Pure feed additive of plants | ZITAN TANG | 2011-11-16 | — | — | CN | disclosed |
| WO-2010114537-A1 | METABOLITES FOR ORAL HEALTH AND USES THEREOF | COLGATE-PALMOLIVE COMPANY (US) | 2010-10-07 | — | — | WO | disclosed |
| CN-101129165-A | Pure feed additive of plants | ZITAN TANG (CN) | 2008-02-27 | — | — | CN | disclosed |
| US-20070118916-A1 | Process for the production of fine chemicals | METANOMICS GMBH (DE) | 2007-05-24 | — | — | US | disclosed |
| CN-1254484-C | Solid-phase synthesis process of octreotide acetate | CHANGCHUN LIFEIN PHARMACEUTICA (CN) | 2006-05-03 | — | — | CN | disclosed |
| EP-0975798-A1 | METHOD TO DIAGNOSE AND TREAT PATHOLOGICAL CONDITIONS RESULTING FROM DEFICIENT ION TRANSPORT SUCH AS PSEUDOHYPOALDOSTERONISM TYPE-1 | YALE UNIVERSITY (US) | 2000-02-02 | — | — | EP | disclosed |
| EP-0946729-A2 | PROTEINS WITH ENHANCED LEVELS OF ESSENTIAL AMINO ACIDS | PIONEER HI-BRED INTERNATIONAL, INC. (US) | 1999-10-06 | — | — | EP | disclosed |
| US-5888768-A | CULTURE PRODUCT; GENETIC ENGINEERING | ZYMOGENETICS, INC. (US) | 1999-03-30 | — | — | US | disclosed |
| WO-1998040516-A1 | METHOD TO DIAGNOSE AND TREAT PATHOLOGICAL CONDITIONS RESULTING FROM DEFICIENT ION TRANSPORT SUCH AS PSEUDOHYPOALDOSTERONISM TYPE-1 | YALE UNIVERSITY (US) | 1998-09-17 | — | — | WO | disclosed |
| WO-1998020133-A2 | PROTEINS WITH ENHANCED LEVELS OF ESSENTIAL AMINO ACIDS | PIONEER HI-BRED INTERNATIONAL, INC. (US) | 1998-05-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070118916-A1 | Process for the production of fine chemicals | POLRMT, POLI, POLM | KDM4E 3359/4885MAPT 448/4885KMT2A 1253/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.