Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.53 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | AGXT | P21549 | 2/20 | 0.43 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 1/20 | 0.41 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8953941 | 0.86 | TAAR1 (0.50) | TAAR1IDO1AGXTCNR1SIGMAR1 | |
| SCHEMBL5240585 | 0.82 | TAAR1 (0.68) | TAAR1IDO1AGXTSIGMAR1MAOB | |
| SCHEMBL19524669 | 0.80 | TAAR1 (0.65) | TAAR1IDO1AGXTSIGMAR1MAOB | |
| SCHEMBL5490784 | 0.79 | TAAR1 (0.55) | TAAR1IDO1AGXTSMN1; SMN2 | |
| SCHEMBL11134683 | 0.79 | TAAR1 (0.59) | TAAR1IDO1AGXTCNR1SIGMAR1 | |
| SCHEMBL4399626 | 0.77 | TAAR1 (0.74) | TAAR1IDO1AGXTSIGMAR1MAOB | |
| SCHEMBL13569139 | 0.76 | TAAR1 (0.61) | TAAR1IDO1AGXTSIGMAR1MAOB | |
| SCHEMBL82275 | 0.76 | TAAR1 (0.61) | TAAR1IDO1AGXTSIGMAR1MAOB | |
| SCHEMBL5483581 | 0.76 | TAAR1 (0.46) | TAAR1CNR1SIGMAR1CYP11B1CYP11B2 | |
| SCHEMBL5139428 | 0.76 | TAAR1 (0.61) | TAAR1IDO1AGXTSIGMAR1MAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |