Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HMOX1 | P09601 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.39 |
| ▸ | RELA | Q04206 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.38 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.38 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.38 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.36 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.36 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5490192 | 0.94 | TAAR1 (0.45) | TAAR1HTR2AHMOX1NPC1NFKB1 | |
| SCHEMBL17442485 | 0.89 | MAOB (0.36) | TAAR1HTR2A | |
| SCHEMBL5488977 | 0.86 | TAAR1 (0.50) | TAAR1HTR2AHMOX1CYP11B1CYP11B2 | |
| SCHEMBL8953875 | 0.83 | TAAR1 (0.44) | TAAR1HTR2AHMOX1NPC1NFKB1 | |
| SCHEMBL5488470 | 0.80 | TAAR1 (0.48) | TAAR1L3MBTL1 | |
| SCHEMBL4298278 | 0.80 | CA1 (0.34) | TAAR1HTR2AL3MBTL1 | |
| SCHEMBL5238701 | 0.78 | TAAR1 (0.62) | TAAR1HTR2AHMOX1NPC1NFKB1 | |
| SCHEMBL7904900 | 0.78 | TAAR1 (0.62) | TAAR1HTR2AHMOX1NPC1NFKB1 | |
| SCHEMBL1599233 | 0.77 | SIGMAR1 (0.48) | HTR2AMAPK1SMN1; SMN2L3MBTL1SIGMAR1 | |
| SCHEMBL2872396 | 0.77 | KCNH2 (0.34) | NFKB1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7291747-B2 | Silicon compounds and process for preparation thereof | CHISSO CORPORATION (JP) | 2007-11-06 | — | — | US | disclosed |
| US-20040143081-A1 | Novel silicon compounds and process for preparation thereof | JNC CORPORATION (JP) | 2004-07-22 | — | — | US | disclosed |