Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20916878 | 0.87 | HDAC6 (0.38) | HDAC6HDAC1HDAC2DGAT1CA14 | |
| SCHEMBL7856537 | 0.76 | HDAC6 (0.33) | HDAC6HDAC1HDAC2DGAT1 | |
| SCHEMBL206709 | 0.75 | HDAC6 (0.37) | HDAC6HDAC1HDAC2DGAT1CA14 | |
| SCHEMBL7024160 | 0.75 | HDAC6 (0.41) | HDAC6HDAC1HDAC2DGAT1CA14 | |
| SCHEMBL10558566 | 0.74 | NFKB1 (0.44) | HDAC6HDAC1HDAC2CA14 | |
| SCHEMBL8098483 | 0.73 | HDAC6 (0.40) | HDAC6HDAC1HDAC2DGAT1CA14 | |
| SCHEMBL24700452 | 0.71 | HDAC6 (0.39) | HDAC6HDAC1HDAC2DGAT1CA14 | |
| SCHEMBL15112990 | 0.71 | HDAC6 (0.39) | HDAC6HDAC1HDAC2DGAT1CA14 | |
| SCHEMBL1462387 | 0.70 | HDAC6 (0.38) | HDAC6HDAC1HDAC2DGAT1CA14 | |
| SCHEMBL5345858 | 0.70 | HDAC6 (0.34) | HDAC6HDAC1HDAC2DGAT1CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1015439-B1 | PRENYL TRANSFERASE INHIBITORS | SOD CONSEILS RECH APPLIC (FR) | 2007-04-11 | — | — | EP | disclosed |
| EP-1676855-A2 | Prenyl transferase inhibitors | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES S.A. (S.C.R.A.S.) (FR) | 2006-07-05 | — | — | EP | disclosed |
| US-6313109-B2 | ANTIPROLIFERATIVE AGENTS; TREATING TUMORS, RESTENOSIS | SOCIETE DE CONSEILS DE RECHERCHES D'APPLICATIONS SCIENTIFIQUES, SAS (FR) | 2001-11-06 | — | — | US | disclosed |
| US-20010000344-A1 | Prenyl transferase inhibitors | BIOMEASURE INCORPORATED | 2001-04-19 | — | — | US | disclosed |
| EP-1087981-A2 | PRENYL TRANSFERASE INHIBITORS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES S.A.S. (FR) | 2001-04-04 | — | — | EP | disclosed |
| US-6180619-B1 | TREATING TUMORS OR RESTENOSIS | BIOMEASURE, INCORPORATED | 2001-01-30 | — | — | US | disclosed |
| WO-1999065922-A2 | PRENYL TRANSFERASE INHIBITORS | SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES S.A.S. (FR) | 1999-12-23 | — | — | WO | disclosed |
| US-5767274-A | TREATING TUMORS OR RESTENOSIS | BIOMEASURE, INCORPORATED (US) | 1998-06-16 | — | — | US | disclosed |
| EP-0017536-B1 | PROCESS FOR THE PREPARATION OF SOMATOSTATINE | SANOFI S.A. (FR) | 1983-03-23 | — | — | EP | disclosed |
| EP-0017536-A2 | Process for the preparation of somatostatine | SANOFI S.A. (FR) | 1980-10-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010000344-A1 | Prenyl transferase inhibitors | FNTA, FNTB, RCE1 | HDAC6 1610/4885HDAC1 1189/4885HDAC2 2386/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.