SCHEMBL548269

SCHEMBL548269

CCCCCC1CCC(c2ccccc2)CC1

nearest known ligand 0.55

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DRD2 P14416 2/20 0.49
CYP2C9 P11712 2/20 0.46
MAPT P10636 4/20 0.44
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
ALDH1A1 P00352 2/20 0.44
LMNA P02545 2/20 0.44
MAPK1 P28482 2/20 0.44
SPHK1 Q9NYA1 2/20 0.44
GAA P10253 3/20 0.43
KDM4E B2RXH2 1/20 0.43
ESR2 Q92731 1/20 0.42
NPC1 O15118 1/20 0.42
CYP1A2 P05177 1/20 0.42
CYP2D6 P10635 1/20 0.42
HPGD P15428 1/20 0.42
TSHR P16473 1/20 0.42
CYP2C19 P33261 1/20 0.42
RAB9A P51151 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL548268 1.00 DRD2 (0.49) DRD2CYP2C9MAPTMEN1KMT2A
SCHEMBL28160606 0.98 DRD2 (0.47) DRD2CYP2C9MAPTMEN1KMT2A
SCHEMBL10348257 0.98 DRD2 (0.47) DRD2CYP2C9MAPTMEN1KMT2A
SCHEMBL9751722 0.98 DRD2 (0.47) DRD2CYP2C9MAPTMEN1KMT2A
SCHEMBL7732963 0.97 DRD2 (0.46) DRD2CYP2C9MAPTMEN1KMT2A
SCHEMBL8138102 0.95 DRD2 (0.45) DRD2CYP2C9MAPTMEN1KMT2A
SCHEMBL8138097 0.95 DRD2 (0.45) DRD2CYP2C9MAPTMEN1KMT2A
SCHEMBL7732647 0.95 DRD2 (0.45) DRD2CYP2C9MAPTMEN1KMT2A
SCHEMBL1789931 0.95 DRD2 (0.50) DRD2CYP2C9MAPTMEN1KMT2A
SCHEMBL1791654 0.95 DRD2 (0.50) DRD2CYP2C9MAPTMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116535303-B Method for synthesizing 4- (4-alkyl cyclohexyl) aryl ketone by replacing dichloroethane with methylcyclohexane 山东齐阳光电科技有限公司 2023-09-05 CN claimed
CN-116535303-A Method for synthesizing 4- (4-alkyl cyclohexyl) aryl ketone by replacing dichloroethane with methylcyclohexane 山东齐阳光电科技有限公司 2023-08-04 CN claimed
CN-107987849-A A kind of liquid crystal aligning immunomodulator compounds and preparation method thereof 烟台丰鲁精细化工有限责任公司 2018-05-04 CN claimed
JP-60078931-A None JP disclosed
US-20230400721-A1 METHOD FOR PRODUCING LIQUID CRYSTAL MATERIAL, METHOD FOR EVALUATING LIQUID CRYSTAL MATERIAL, MEASUREMENT APPARATUS THEREFOR, AND LIQUID CRYSTAL MATERIAL DIC CORPORATION (JP) 2023-12-14 US disclosed
CN-116535303-B Method for synthesizing 4- (4-alkyl cyclohexyl) aryl ketone by replacing dichloroethane with methylcyclohexane 山东齐阳光电科技有限公司 2023-09-05 CN disclosed
CN-116535303-A Method for synthesizing 4- (4-alkyl cyclohexyl) aryl ketone by replacing dichloroethane with methylcyclohexane 山东齐阳光电科技有限公司 2023-08-04 CN disclosed
EP-2080750-B1 RADIATION-SENSITIVE COMPOSITION MITSUBISHI GAS CHEMICAL CO (JP) 2020-07-29 EP disclosed
CN-109476999-A Electronics switching element 默克专利股份有限公司 2019-03-15 CN disclosed
CN-108885373-A Liquid crystal aligning agent, liquid crystal alignment film, and liquid crystal display element containing polymer having site having isocyanate group and/or blocked isocyanate group and site having photoreactive activity and crosslinking agent 日产化学工业株式会社 2018-11-23 CN disclosed
CN-103339565-B Photochromic compound and composition 光学转变公司 2018-08-14 CN disclosed
EP-0260153-A2 Cyclohexylphenylpyridazines Chisso Corporation (JP) 1988-03-16 EP disclosed
EP-0184012-B1 LIQUID CRYSTAL COMPOSITIONS BAYER AG (DE) 1988-01-07 EP disclosed
EP-0155317-B1 LIQUID CRYSTAL MIXTURES AND NEW ANISOTROPIC COMPOUNDS THEREFOR MERCK PATENT GmbH (DE) 1987-07-08 EP disclosed
EP-0184012-A1 Liquid crystal compositions BAYER AG (DE) 1986-06-11 EP disclosed
US-4572794-A Acetonitriles, their preparation, and dielectrics and electro-optical display elements containing them MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1986-02-25 US disclosed
JP-S6078931-A PRODUCTION OF PHENYLCYCLOHEXANE DERIVATIVE SEIKO EPSON CORP 1985-05-04 JP disclosed
EP-0030277-B1 PARTIALLY HYDROGENATED OLIGO-1,4-PHENYLENES, DIELECTRICS CONTAINING THEM AND ELECTRO-OPTICAL INDICATING DEVICE MERCK PATENT GmbH (DE) 1983-07-27 EP disclosed
US-4331552-A Liquid crystalline, partially hydrogenated oligo-1,4-phenylenes and dielectrics and electro-optical display elements containing them MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1982-05-25 US disclosed
US-4130502-A Liquid crystalline cyclohexane derivatives MERCK PATENT GESELLSCHAFT MIT (DE) 1978-12-19 US disclosed