SCHEMBL5482698

SCHEMBL5482698

Cc1c(Cl)ccc(O[C@H](C)C(=O)Nc2ccccc2)c1Cl

nearest known ligand 0.54

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.52
ALDH1A1 P00352 1/20 0.52
GAA P10253 1/20 0.52
PKM P14618 1/20 0.52
LMNA P02545 2/20 0.51
TSHR P16473 2/20 0.51
MAPK1 P28482 1/20 0.51
HPGD P15428 1/20 0.50
HTT P42858 1/20 0.48
NOTUM Q6P988 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
L3MBTL1 Q9Y468 1/20 0.47
MEN1 O00255 1/20 0.47
KMT2A Q03164 1/20 0.47
RXFP1 Q9HBX9 1/20 0.47
KLK7 P49862 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3062871 1.00 KDM4E (0.52) KDM4EALDH1A1GAAPKMLMNA
SCHEMBL7654105 1.00 KDM4E (0.52) KDM4EALDH1A1GAAPKMLMNA
SCHEMBL55118 1.00 KDM4E (0.52) KDM4EALDH1A1GAAPKMLMNA
SCHEMBL11077507 0.91 KDM4E (0.53) KDM4EALDH1A1GAAPKMLMNA
SCHEMBL8465568 0.91 KDM4E (0.53) KDM4EALDH1A1GAAPKMLMNA
SCHEMBL11082625 0.90 ALDH1A1 (0.55) KDM4EALDH1A1GAAPKMLMNA
SCHEMBL11079681 0.90 ALDH1A1 (0.62) KDM4EALDH1A1GAAPKMLMNA
SCHEMBL11076398 0.88 KLK7 (0.47) KDM4EALDH1A1GAAPKMLMNA
SCHEMBL11081961 0.88 ALDH1A1 (0.67) KDM4EALDH1A1GAAPKMLMNA
SCHEMBL11080607 0.88 NPSR1 (0.56) KDM4EALDH1A1GAAPKMLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20070197386-A1 Enhancers for Water Soluble Selective Auxin Type Herbicides W. NEUDORFF GMBH KG (DE) 2007-08-23 US claimed
US-6746684-B2 CORE COATED WITH A RESIN WALL MATERIAL FORMED BY WATER-SOLUBLE MELAMINE-FORMALDEHYDE RESIN TO POLYCONDENSATION IN A DISPERSANT OF CONDENSATION PRODUCT OF (ALKYL)NAPHTHALENE-SULFONIC ACID AND FORMALDEHYDE SYNGENTA CROP PROTECTION, INC. 2004-06-08 US disclosed
EP-1170997-B1 MICROENCAPSULATED SOLID PESTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2003-03-26 EP disclosed
US-20020081337-A1 Microencapsulated solid pesticides MERRILL LYNCH CAPITAL, A DIVISION OF MERRILL LYNCH 2002-06-27 US disclosed
EP-1170997-A1 MICROENCAPSULATED SOLID PESTICIDES Syngenta Participations AG (CH) 2002-01-16 EP disclosed
WO-2000062612-A1 MICROENCAPSULATED SOLID PESTICIDES SYNGENTA PARTICIPATIONS AG (CH) 2000-10-26 WO disclosed