Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA7 | P43166 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.36 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.32 |
| ▸ | GCGR | P47871 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1399041 | 0.90 | TSHR (0.46) | TSHRMAPK1MAPTRECQLCA12 | |
| SCHEMBL522175 | 0.82 | TSHR (0.61) | TSHRMAPK1MAPTRECQLCA12 | |
| SCHEMBL23169065 | 0.82 | TSHR (0.53) | TSHRMAPK1MAPTRECQLCA12 | |
| SCHEMBL521688 | 0.82 | TSHR (0.58) | TSHRMAPK1MAPTRECQLCA12 | |
| SCHEMBL1719721 | 0.80 | TSHR (0.59) | TSHRMAPK1MAPTRECQLCA12 | |
| SCHEMBL9766021 | 0.80 | TSHR (0.51) | TSHRMAPK1MAPTRECQLCA12 | |
| SCHEMBL9874822 | 0.78 | TSHR (0.50) | TSHRMAPK1MAPTRECQLCA12 | |
| SCHEMBL7198377 | 0.78 | TSHR (0.57) | TSHRMAPK1MAPTRECQLCA12 | |
| SCHEMBL11288719 | 0.77 | TSHR (0.49) | TSHRMAPK1MAPTRECQLCA12 | |
| SCHEMBL505263 | 0.77 | TSHR (0.52) | TSHRMAPK1MAPTRECQLCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4486355-A | INSECTICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-12-04 | — | — | US | claimed |
| US-7195835-B2 | Proton conducting membrane for fuel cells | UCHICAGO ARGONNE, LLC (US) | 2007-03-27 | — | — | US | disclosed |
| US-20060094792-A1 | Proton conducting membrane for fuel cells | THE UNIVERSITY OF CHICAGO | 2006-05-04 | — | — | US | disclosed |
| US-6977122-B2 | Proton conducting membrane for fuel cells | THE UNIVERSITY OF CHICAGO (US) | 2005-12-20 | — | — | US | disclosed |
| US-20030035991-A1 | Proton conducting membrane for fuel cells | THE UNIVERSITY OF CHICAGO | 2003-02-20 | — | — | US | disclosed |
| WO-2002078110-A2 | DENDRIMER-CONTAINING PROTON CONDUCTING MEMBRANE FOR FUEL CELLS | UNIVERSITY OF CHICAGO (US) | 2002-10-03 | — | — | WO | disclosed |
| EP-0266947-B1 | HALOGENATED ESTERS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-12-04 | — | — | EP | disclosed |
| EP-0181284-B1 | AMINO ACID ESTERS | SANDOZ AG (CH) | 1990-02-07 | — | — | EP | disclosed |
| US-4868209-A | AGRICULTURAL INSECTICIDES, CYCLOPROPANE CARBOXYLIC ACIDS | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-09-19 | — | — | US | disclosed |
| US-4853414-A | 1-/2-ALKOXY-3,5-DIFLUOROBENZYL ESTERS OF 2,2-DIMETHYL-3-ALKYLCYCLOPROPIONIC ACID; INSECTICIDES; PESTICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-08-01 | — | — | US | disclosed |
| EP-0054360-B1 | FLUOROBENZYL CYCLOPROPANE CARBOXYLATES, THEIR PREPARATION, COMPOSITIONS COMPRISING THEM AND THEIR USE AS INSECTICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1985-06-05 | — | — | EP | disclosed |
| US-4486355-A | INSECTICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-12-04 | — | — | US | disclosed |
| EP-0032121-B1 | SUBSTITUTED TETRAFLUOROBENZYL ALCOHOLS AND HALIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1984-05-16 | — | — | EP | disclosed |
| US-4385070-A | CYCLOPROPANE DERIVATIVES AS INSECTICIDES | IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) | 1983-05-24 | — | — | US | disclosed |
| US-4370346-A | INSECTICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1983-01-25 | — | — | US | disclosed |
| EP-0060617-A1 | Fluorobenzyl cyclopropane carboxylates, their preparation, compositions and use as insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-09-22 | — | — | EP | disclosed |
| EP-0054360-A2 | Fluorobenzyl cyclopropane carboxylates, their preparation, compositions comprising them and their use as insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-06-23 | — | — | EP | disclosed |
| EP-0016513-B1 | ESTERS OF HALOGENATED SUBSTITUTED CYCLOPROPANOIC ACIDS, THEIR PREPARATION AND USE AS INSECTICIDES | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1982-06-23 | — | — | EP | disclosed |
| EP-0032121-A2 | Substituted tetrafluorobenzyl alcohols and halides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1981-07-15 | — | — | EP | disclosed |
| EP-0016513-A2 | Esters of halogenated substituted cyclopropanoic acids, their preparation and use as insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1980-10-01 | — | — | EP | disclosed |