Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2R | P25116 | 17/20 | 0.68 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL1732333 | 0.96 | F2R (0.63) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1730685 | 0.94 | F2R (0.60) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL5485502 | 0.93 | F2R (0.59) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1732508 | 0.93 | F2R (0.59) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1731096 | 0.92 | F2R (0.57) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1731033 | 0.91 | F2R (0.68) | F2RKDM4EMAPT | |
| Bromide SCHEMBL1732092 | 0.91 | F2R (0.57) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1733089 | 0.90 | F2R (0.55) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1729420 | 0.89 | F2R (0.70) | F2RKDM4ENPC1MAPTRAB9A | |
| Bromide SCHEMBL1732007 | 0.89 | F2R (0.54) | F2RKDM4ENPC1MAPTRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107643654-B | Photosensitive resin composition, cured film, color filter, and method for producing cured film | 东京应化工业株式会社 | 2023-07-07 | — | — | CN | disclosed |
| CN-113166370-A | Polycarboxylic acid compounds for treating fibrous substrates based on amino acids, especially hair | 迈图高新材料公司 | 2021-07-23 | — | — | CN | disclosed |
| US-10617617-B1 | Polycarboxylic acid compounds for the treatment of fibrious amino acid based substrates, especially hair | MOMENTIVE PERFORMANCE MATERIALS INC. (US) | 2020-04-14 | — | — | US | disclosed |
| US-9422587-B2 | Selection of improved microbial strains for production of succinic acid from glycerol | THE UNIVERSITY OF MANCHESTER (GB) | 2016-08-23 | — | — | US | disclosed |
| EP-2699701-A1 | SELECTION OF IMPROVED MICROBIAL STRAINS FOR PRODUCTION OF SUCCINIC ACID FROM GLYCEROL | The University of Manchester (GB) | 2014-02-26 | — | — | EP | disclosed |
| US-20140038229-A1 | SELECTION OF IMPROVED MICROBIAL STRAINS FOR PRODUCTION OF SUCCINIC ACID FROM GLYCEROL | THE UNIVERSITY OF MANCHESTER (GB) | 2014-02-06 | — | — | US | disclosed |
| WO-2012143736-A1 | SELECTION OF IMPROVED MICROBIAL STRAINS FOR PRODUCTION OF SUCCINIC ACID FROM GLYCEROL | THE UNIVERSITY OF MANCHESTER (GB) | 2012-10-26 | — | — | WO | disclosed |
| WO-2007103819-A2 | METHOD, APPARATUS AND COMPOSITIONS FOR FIREFIGHTING | PYRO TECH, INC. (US) | 2007-09-13 | — | — | WO | disclosed |
| US-7244730-B2 | 2-iminopyrrolidine derivatives | EISAI CO., LTD (JP) | 2007-07-17 | — | — | US | disclosed |
| US-20050245592-A1 | 2-Iminopyrrolidine derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2005-11-03 | — | — | US | disclosed |
| US-20050004204-A1 | 2-Iminopyrrolidine derivatives | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2005-01-06 | — | — | US | disclosed |
| EP-1391451-A1 | 2-IMINOPYRROLIDINE DERIVATES | Eisai Co., Ltd. (JP) | 2004-02-25 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050245592-A1 | 2-Iminopyrrolidine derivatives | H1-2, H1-3, H1-0 | F2R 2290/4885KDM4E 3161/4885NPC1 4243/4885 |
| US-20050004204-A1 | 2-Iminopyrrolidine derivatives | H1-2, H1-3, H1-0 | F2R 2289/4885KDM4E 3132/4885NPC1 4254/4885 |
| US-10617617-B1 | Polycarboxylic acid compounds for the treatment of fibrious amino acid based substrates, especially hair | ABAT, PCCA, FAH | F2R 4134/4885KDM4E 561/4885NPC1 1671/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.