Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 2/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.38 |
| ▸ | KDR | P35968 | 9/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 3/20 | 0.35 |
| ▸ | PAK1 | Q13153 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 3/20 | 0.35 |
| ▸ | PTK2B | Q14289 | 1/20 | 0.35 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.34 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.34 |
| ▸ | CDK2 | P24941 | 1/20 | 0.34 |
| ▸ | CDK9 | P50750 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6098675 | 0.91 | BTK (0.39) | GRM4BTKKDRPTK2PAK1 | |
| SCHEMBL5407220 | 0.85 | PAK1 (0.38) | GRM4KDRPAK1SYK | |
| SCHEMBL31672445 | 0.80 | KDR (0.44) | KDRPAK1CCNT1CCNE1CDK2 | |
| SCHEMBL10151156 | 0.80 | KDR (0.44) | KDRPAK1CCNT1CCNE1CDK2 | |
| SCHEMBL31672441 | 0.70 | KDR (0.46) | KDRPAK1CCNT1CCNE1CDK2 | |
| SCHEMBL2877133 | 0.70 | KDR (0.46) | KDRPAK1CCNT1CCNE1CDK2 | |
| SCHEMBL31672487 | 0.69 | KDR (0.46) | KDRCCNT1CCNE1CDK2CDK9 | |
| SCHEMBL10151171 | 0.69 | KDR (0.46) | KDRCCNT1CCNE1CDK2CDK9 | |
| Hydrochloric Acid SCHEMBL1687059 | 0.68 | KDR (0.46) | KDRCCNT1CCNE1CDK2CDK9 | |
| SCHEMBL589714 | 0.68 | KDR (0.41) | KDRCCNT1CCNE1CDK2CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070015756-A1 | Chemical compounds | NOVARTIS AG (CH) | 2007-01-18 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070015756-A1 | Chemical compounds | KDR, FLT4, FLT1 | GRM4 4217/4885BTK 242/4885KDR 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.