Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 6/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.36 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.34 |
| ▸ | DNM1 | Q05193 | 5/20 | 0.31 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1315871 | 1.00 | TSHR (0.42) | TSHRTHRBZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL1317936 | 0.90 | TSHR (0.38) | TSHRZDHHC20ZDHHC2ALDH1A1LMNA | |
| SCHEMBL28796617 | 0.81 | TSHR (0.42) | TSHRTHRBZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL11383136 | 0.81 | TSHR (0.42) | TSHRTHRBZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL812114 | 0.81 | TSHR (0.42) | TSHRTHRBZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL28112915 | 0.81 | TSHR (0.42) | TSHRTHRBZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL1315956 | 0.81 | TSHR (0.42) | TSHRTHRBZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL1315286 | 0.79 | — | — | |
| SCHEMBL5484219 | 0.79 | TSHR (0.41) | TSHRTHRBZDHHC20ZDHHC2ALDH1A1 | |
| SCHEMBL1317866 | 0.79 | TSHR (0.41) | TSHRTHRBZDHHC20ZDHHC2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1596193-B1 | Novel stationary phases for use in high-performance liquid chromatography | AGILENT TECHNOLOGIES INC (US) | 2007-06-20 | — | — | EP | disclosed |
| CN-1759931-A | Novel stationary phases for use in high-performance liquid chromatography | AGILENT TECHNOLOGIES INC (US) | 2006-04-19 | — | — | CN | disclosed |
| US-20060076296-A1 | Novel stationary phases for use in high-performance liquid chromatography | AGILENT TECHNOLOGIES, INC. | 2006-04-13 | — | — | US | disclosed |
| EP-1596193-A1 | Novel stationary phases for use in high-performance liquid chromatography | Agilent Technologies, Inc. (US) | 2005-11-16 | — | — | EP | disclosed |
| US-20050242038-A1 | Novel stationary phases for use in high-performance liquid chromatography | AGILENT TECHNOLOGIES, INC. | 2005-11-03 | — | — | US | disclosed |