Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OXTR | P30559 | 20/20 | 0.81 |
| ▸ | AVPR2 | P30518 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9975177 | 1.00 | OXTR (0.81) | OXTRAVPR2 | |
| SCHEMBL1598224 | 1.00 | OXTR (0.81) | OXTRAVPR2 | |
| SCHEMBL1599335 | 0.89 | OXTR (1.00) | OXTRAVPR2 | |
| SCHEMBL11982199 | 0.88 | OXTR (0.73) | OXTRAVPR2 | |
| SCHEMBL1597826 | 0.88 | OXTR (0.73) | OXTRAVPR2 | |
| SCHEMBL9975178 | 0.88 | OXTR (0.73) | OXTRAVPR2 | |
| SCHEMBL16531863 | 0.88 | OXTR (0.73) | OXTRAVPR2 | |
| SCHEMBL9975175 | 0.87 | OXTR (0.80) | OXTRAVPR2 | |
| SCHEMBL1598441 | 0.87 | OXTR (0.80) | OXTRAVPR2 | |
| SCHEMBL11982229 | 0.87 | OXTR (0.80) | OXTRAVPR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070254888-A1 | Piperazinediones as Oxytocin Receptor Antagonists | GLAXO GROUP LIMITED (GB) | 2007-11-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070254888-A1 | Piperazinediones as Oxytocin Receptor Antagonists | OXTR, PRLHR, AVPR2 | OXTR 1/4885AVPR2 3/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.