Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | BLM | P54132 | 3/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.38 |
| ▸ | GABRP | O00591 | 3/20 | 0.38 |
| ▸ | GABRD | O14764 | 3/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.38 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.38 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.38 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.38 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.38 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.38 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.38 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.38 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.38 |
| ▸ | GABRE | P78334 | 3/20 | 0.38 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.38 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.38 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.38 |
| ▸ | GABRQ | Q9UN88 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5483404 | 0.75 | FOLH1 (0.39) | FOLH1LMNABLMCYP1A2GABRP | |
| SCHEMBL4135921 | 0.74 | FOLH1 (0.44) | FOLH1GRM3 | |
| SCHEMBL4143577 | 0.71 | FOLH1 (0.51) | FOLH1GRM3CPB2 | |
| SCHEMBL16529247 | 0.70 | FOLH1 (0.43) | FOLH1CYP1A2GSRGRM8GRM6 | |
| SCHEMBL1231740 | 0.62 | CYP1A2 (0.50) | FOLH1CYP1A2GABRPGABRDGABRA1 | |
| SCHEMBL27935875 | 0.62 | TET2 (0.46) | FOLH1CYP1A2GABRPGABRDGABRA1 | |
| SCHEMBL10629764 | 0.62 | LMNA (0.56) | FOLH1LMNABLMCYP1A2GABRP | |
| Glutamic Acid SCHEMBL6850406 | 0.61 | GSR (0.75) | FOLH1LMNABLMCYP1A2GABRP | |
| D-Glutamate SCHEMBL4414452 | 0.61 | GSR (0.75) | FOLH1LMNABLMCYP1A2GABRP | |
| D-Glutamate SCHEMBL20578252 | 0.61 | GSR (0.75) | FOLH1LMNABLMCYP1A2GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070041934-A1 | Dendrimer based compositions and methods of using the same | REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2007-02-22 | — | — | US | disclosed |