Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8387200 | 0.81 | — | — | |
| SCHEMBL9702134 | 0.71 | ALDH1A1 (0.43) | — | |
| SCHEMBL13381787 | 0.67 | TDP1 (0.43) | CYP3A4 | |
| SCHEMBL10099855 | 0.67 | TDP1 (0.43) | CYP3A4 | |
| SCHEMBL28933423 | 0.67 | CYP3A4 (0.32) | CYP3A4 | |
| SCHEMBL29908265 | 0.66 | TLR2 (0.34) | CYP3A4 | |
| SCHEMBL19566343 | 0.66 | CYP3A4 (0.38) | CYP3A4 | |
| SCHEMBL3208469 | 0.66 | CYP3A4 (0.34) | CYP3A4 | |
| SCHEMBL940665 | 0.66 | — | — | |
| SCHEMBL25723519 | 0.64 | TLR2 (0.33) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1808183-A2 | Chemically-defined non-polymeric valency platform molecules and conjugates thereof | LA JOLLA PHARMACEUTICAL COMPANY (US) | 2007-07-18 | — | — | EP | disclosed |
| EP-0642798-A2 | Chemically-defined non-polymeric valency platform molecules and conjugates thereof | LA JOLLA PHARMACEUTICAL COMPANY (CA) | 1995-03-15 | — | — | EP | disclosed |