Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 13/20 | 0.58 |
| ▸ | ADORA2A | P29274 | 13/20 | 0.58 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.55 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | HPGD | P15428 | 2/20 | 0.49 |
| ▸ | CASP1 | P29466 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31636814 | 0.77 | POLB (0.56) | ADORA1ADORA2AADORA2BHSD17B10KDM4E | |
| SCHEMBL5483521 | 0.76 | KDM4E (0.64) | ADORA1ADORA2AHSD17B10KDM4EALDH1A1 | |
| SCHEMBL5483588 | 0.74 | SQOR (0.54) | ADORA1ADORA2AADORA2BHSD17B10KDM4E | |
| SCHEMBL28383673 | 0.73 | KDM4E (0.66) | ADORA1ADORA2AHSD17B10KDM4EALDH1A1 | |
| SCHEMBL6440715 | 0.73 | ADORA1 (0.72) | ADORA1ADORA2AADORA2B | |
| SCHEMBL31139648 | 0.72 | ADORA2A (0.53) | ADORA1ADORA2AADORA2BHSD17B10KDM4E | |
| SCHEMBL5480727 | 0.72 | ADORA2A (0.54) | ADORA1ADORA2AADORA2BKDM4EALDH1A1 | |
| SCHEMBL3369169 | 0.72 | ADORA1 (0.71) | ADORA1ADORA2AADORA2BHSD17B10KDM4E | |
| SCHEMBL15840888 | 0.71 | ADORA1 (0.64) | ADORA1ADORA2AADORA2BHSD17B10 | |
| SCHEMBL27886268 | 0.71 | KDM4E (0.60) | ADORA1ADORA2AADORA2BHSD17B10KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070287738-A1 | Substituted Cyanopyridines as protein kinase inhibitors | WYETH | 2007-12-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070287738-A1 | Substituted Cyanopyridines as protein kinase inhibitors | CNKSR1, MAP3K1, MAP3K6 | ADORA1 671/4885ADORA2A 1009/4885ADORA2B 1635/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.